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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WASL All Species: 29.7
Human Site: S456 Identified Species: 50.26
UniProt: O00401 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00401 NP_003932.3 505 54827 S456 S V A D G Q E S T P P T P A P
Chimpanzee Pan troglodytes XP_001148606 495 53819 S446 S V A D G Q E S T P P T P A P
Rhesus Macaque Macaca mulatta XP_001085180 435 47267 G399 A P T S G I V G A L M E V M Q
Dog Lupus familis XP_532445 505 54680 S456 S V S D G Q E S T P P T P A P
Cat Felis silvestris
Mouse Mus musculus Q91YD9 501 54256 S452 S V S D G Q E S T P P T P A P
Rat Rattus norvegicus O08816 501 54307 S452 S V S D G Q E S T P P T P A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508405 466 50516 S417 S V S D G Q E S A P P T P A P
Chicken Gallus gallus XP_415994 505 54715 S456 S V S D G Q E S A P P T P A P
Frog Xenopus laevis NP_001084852 512 55702 T462 S V P D E A D T V P S T P A P
Zebra Danio Brachydanio rerio Q6PFT9 646 70983 K610 N P A G S V R K V A P P P P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651637 527 56956 L480 K P A K E R E L G S Q R N S D
Honey Bee Apis mellifera XP_392742 528 58877 N484 P V S N E A K N K T T S T F Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181262 492 52224 E446 K V T Q A E K E E S P A S T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12446 633 67553 N595 S P P A A A G N G G T P G G P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 85.5 97 N.A. 95.4 95.2 N.A. 86.1 91.2 74.4 20.1 N.A. 35.6 34.8 N.A. 38.4
Protein Similarity: 100 98 85.7 98 N.A. 96.8 96.8 N.A. 87.3 94 83.4 31.4 N.A. 49.7 51.1 N.A. 51.4
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 53.3 20 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 93.3 93.3 66.6 26.6 N.A. 26.6 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 29 8 15 22 0 0 22 8 0 8 0 58 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 58 0 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 22 8 58 8 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 8 58 0 8 8 15 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 15 0 0 8 0 0 15 8 8 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % M
% Asn: 8 0 0 8 0 0 0 15 0 0 0 0 8 0 0 % N
% Pro: 8 29 15 0 0 0 0 0 0 58 65 15 65 8 72 % P
% Gln: 0 0 0 8 0 50 0 0 0 0 8 0 0 0 15 % Q
% Arg: 0 0 0 0 0 8 8 0 0 0 0 8 0 0 0 % R
% Ser: 65 0 43 8 8 0 0 50 0 15 8 8 8 8 0 % S
% Thr: 0 0 15 0 0 0 0 8 36 8 15 58 8 8 0 % T
% Val: 0 72 0 0 0 8 8 0 15 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _