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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
15.45
Human Site:
S1045
Identified Species:
28.33
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S1045
K
S
L
Q
E
M
F
S
G
T
R
A
I
Q
H
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
A130
E
M
F
S
G
T
R
A
I
Q
H
W
L
I
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
Q843
P
L
G
I
P
I
I
Q
P
Y
H
R
D
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
T1016
K
S
L
Q
E
M
F
T
S
T
R
A
I
Q
H
Rat
Rattus norvegicus
NP_001100236
1203
135799
S1014
K
S
L
Q
E
M
F
S
S
T
R
A
I
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
S1045
S
S
L
K
E
M
F
S
G
T
R
E
I
Q
L
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
V1071
D
D
F
P
K
D
Y
V
W
D
A
S
H
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
T1176
E
S
L
R
E
M
F
T
S
T
R
E
I
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
A696
Y
S
A
A
C
Y
A
A
K
T
T
L
M
A
L
Maize
Zea mays
NP_001104931
975
110846
A794
F
G
A
S
C
Y
A
A
K
V
T
L
T
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
A830
F
G
A
A
C
Y
A
A
K
V
T
L
A
A
I
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
I1083
L
G
E
S
A
K
R
I
S
K
S
I
R
L
D
Red Bread Mold
Neurospora crassa
P38671
1423
159642
I1074
G
T
A
S
G
E
N
I
T
L
A
G
N
P
R
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
0
N.A.
86.6
86.6
N.A.
N.A.
N.A.
73.3
0
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
6.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
80
20
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
13.3
0
N.A.
0
0
0
P-Site Similarity:
26.6
6.6
N.A.
6.6
0
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
16
8
0
24
31
0
0
16
24
8
24
0
% A
% Cys:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
0
0
0
8
0
0
8
0
16
% D
% Glu:
16
0
8
0
39
8
0
0
0
0
0
16
0
0
8
% E
% Phe:
16
0
16
0
0
0
39
0
0
0
0
0
0
0
0
% F
% Gly:
8
24
8
0
16
0
0
0
16
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
16
% H
% Ile:
0
0
0
8
0
8
8
16
8
0
0
8
39
8
8
% I
% Lys:
24
0
0
8
8
8
0
0
24
8
0
0
0
0
8
% K
% Leu:
8
8
39
0
0
0
0
0
0
8
0
24
8
8
31
% L
% Met:
0
8
0
0
0
39
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
8
8
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
24
0
0
0
8
0
8
0
0
0
39
0
% Q
% Arg:
0
0
0
8
0
0
16
0
0
0
39
8
8
0
16
% R
% Ser:
8
47
0
31
0
0
0
24
31
0
8
8
0
8
0
% S
% Thr:
0
8
0
0
0
8
0
16
8
47
24
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
24
8
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _