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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
8.18
Human Site:
S1176
Identified Species:
15
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S1176
E
Q
F
V
R
L
H
S
E
P
I
L
Q
D
L
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
L261
C
L
H
S
E
S
I
L
Q
D
L
S
R
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
T974
W
I
S
K
L
Q
D
T
L
K
A
V
P
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
Q1147
Q
F
V
R
L
H
S
Q
P
I
L
E
D
L
A
Rat
Rattus norvegicus
NP_001100236
1203
135799
E1145
Q
F
V
R
L
H
S
E
P
I
L
E
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
Q1176
Q
F
V
A
L
H
S
Q
P
I
L
Q
N
L
S
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
R1202
V
T
V
D
I
M
N
R
V
C
R
E
Q
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
S1307
E
Q
F
V
A
L
H
S
Q
P
I
L
E
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
R827
D
E
M
N
R
I
L
R
E
K
F
V
E
L
Y
Maize
Zea mays
NP_001104931
975
110846
R925
D
T
M
N
K
I
L
R
E
K
F
V
E
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
R961
D
K
L
N
I
I
L
R
E
K
F
V
E
L
Y
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
E1214
E
Q
F
I
K
L
H
E
V
D
L
V
L
R
L
Red Bread Mold
Neurospora crassa
P38671
1423
159642
S1205
D
A
F
I
R
I
H
S
E
D
V
I
G
R
L
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
0
6.6
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
26.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
13.3
6.6
N.A.
6.6
40
40
P-Site Similarity:
46.6
40
N.A.
40
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
0
0
0
8
0
0
0
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
31
0
0
8
0
0
8
0
0
24
0
0
16
8
0
% D
% Glu:
24
8
0
0
8
0
0
16
39
0
0
24
31
8
0
% E
% Phe:
0
24
31
0
0
0
0
0
0
0
24
0
0
16
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
24
31
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
16
31
8
0
0
24
16
8
0
0
0
% I
% Lys:
0
8
0
8
16
0
0
0
0
31
0
0
0
0
0
% K
% Leu:
0
8
8
0
31
24
24
8
8
0
39
16
8
47
39
% L
% Met:
0
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
24
16
0
0
8
0
0
% P
% Gln:
24
24
0
0
0
8
0
16
16
0
0
8
16
8
0
% Q
% Arg:
0
0
0
16
24
0
0
31
0
0
8
0
8
16
0
% R
% Ser:
0
0
8
8
0
8
24
24
0
0
0
8
0
0
8
% S
% Thr:
0
16
0
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
8
0
31
16
0
0
0
0
16
0
8
39
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _