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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLRMT All Species: 4.55
Human Site: S1202 Identified Species: 8.33
UniProt: O00411 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00411 NP_005026.3 1230 138620 S1202 P Q K I L E A S Q L K E T L Q
Chimpanzee Pan troglodytes XP_001172601 311 35421 E287 L E A S Q M K E T L Q V V P K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542220 1024 113870 D1000 P L P T A S R D T R C A L C S
Cat Felis silvestris
Mouse Mus musculus Q8BKF1 1207 136686 S1173 S I K S L K S S E R A L V T K
Rat Rattus norvegicus NP_001100236 1203 135799 L1171 K S L K P S E L A L I T K L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080987 1235 142073 M1202 S S N S K A K M S P E N L R M
Zebra Danio Brachydanio rerio XP_685138 1253 143135 Y1228 S W F L L Q K Y S R R P P V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608565 1369 156753 G1333 D S D F I N D G S V E D L S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311418 877 99587 L853 F Q S S F P N L K F P P L P E
Maize Zea mays NP_001104931 975 110846 L951 F E K S F P K L K F P P L P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFV6 1011 114502 L987 F E Q S F P H L D F P P L P E
Baker's Yeast Sacchar. cerevisiae P13433 1351 153063 R1240 V K I G K L K R S T D L A Q K
Red Bread Mold Neurospora crassa P38671 1423 159642 T1231 L Y L A K I E T G T K V A Q E
Conservation
Percent
Protein Identity: 100 23.4 N.A. 59.1 N.A. 66.9 65.6 N.A. N.A. N.A. 47.8 45.5 N.A. 37 N.A. N.A. N.A.
Protein Similarity: 100 24.2 N.A. 67.7 N.A. 78.2 77.9 N.A. N.A. N.A. 65 63.6 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 20 20 N.A. N.A. N.A. 0 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 N.A. 6.6 N.A. 46.6 20 N.A. N.A. N.A. 6.6 33.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: 30.7 30.8 N.A. 30 26.8 26.2
Protein Similarity: 44.1 46.9 N.A. 47.5 44.5 41.5
P-Site Identity: 6.6 6.6 N.A. 0 0 6.6
P-Site Similarity: 20 26.6 N.A. 20 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 8 8 0 8 0 8 8 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % C
% Asp: 8 0 8 0 0 0 8 8 8 0 8 8 0 0 0 % D
% Glu: 0 24 0 0 0 8 16 8 8 0 16 8 0 0 31 % E
% Phe: 24 0 8 8 24 0 0 0 0 24 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 8 8 8 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 8 24 8 24 8 39 0 16 0 16 0 8 0 31 % K
% Leu: 16 8 16 8 24 8 0 31 0 24 0 16 47 16 0 % L
% Met: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % M
% Asn: 0 0 8 0 0 8 8 0 0 0 0 8 0 0 0 % N
% Pro: 16 0 8 0 8 24 0 0 0 8 24 31 8 31 8 % P
% Gln: 0 16 8 0 8 8 0 0 8 0 8 0 0 16 16 % Q
% Arg: 0 0 0 0 0 0 8 8 0 24 8 0 0 8 0 % R
% Ser: 24 24 8 47 0 16 8 16 31 0 0 0 0 8 8 % S
% Thr: 0 0 0 8 0 0 0 8 16 16 0 8 8 8 0 % T
% Val: 8 0 0 0 0 0 0 0 0 8 0 16 16 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _