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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
5.45
Human Site:
S185
Identified Species:
10
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S185
C
T
R
Q
A
P
E
S
P
W
E
E
Q
L
A
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
K114
Q
M
G
Q
D
G
L
K
L
Q
E
L
F
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
N154
S
K
K
G
T
P
T
N
S
E
E
K
Q
L
A
Rat
Rattus norvegicus
NP_001100236
1203
135799
S152
S
K
K
G
A
P
K
S
S
E
E
E
Q
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
E170
M
S
S
V
P
A
V
E
K
L
Q
E
S
K
S
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
S224
S
G
E
V
S
L
I
S
V
I
S
D
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
I261
F
E
A
I
E
P
Y
I
S
P
L
D
K
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
Maize
Zea mays
NP_001104931
975
110846
E65
F
S
S
S
A
A
A
E
A
V
S
S
E
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
T101
F
R
C
L
S
G
I
T
R
R
E
E
F
S
K
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
D184
D
L
E
T
S
F
K
D
V
N
Y
N
D
K
T
Red Bread Mold
Neurospora crassa
P38671
1423
159642
D162
V
P
P
A
D
Y
L
D
L
F
N
Q
Y
L
D
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
13.3
N.A.
33.3
53.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
20
N.A.
53.3
66.6
N.A.
N.A.
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
13.3
N.A.
13.3
0
6.6
P-Site Similarity:
0
26.6
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
24
16
8
0
8
0
0
0
0
8
31
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
16
0
0
0
16
8
8
8
% D
% Glu:
0
8
16
0
8
0
8
16
0
16
39
31
8
0
0
% E
% Phe:
24
0
0
0
0
8
0
0
0
8
0
0
16
0
0
% F
% Gly:
0
8
8
16
0
16
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
16
8
0
8
0
0
0
0
0
% I
% Lys:
0
16
16
0
0
0
16
8
8
0
0
8
16
16
16
% K
% Leu:
0
8
0
8
0
8
16
0
16
8
8
8
0
31
8
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
8
8
0
0
0
% N
% Pro:
0
8
8
0
8
31
0
0
8
8
0
0
0
0
0
% P
% Gln:
8
0
0
16
0
0
0
0
0
8
8
8
24
0
0
% Q
% Arg:
0
8
8
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
24
16
16
8
24
0
0
24
24
0
16
8
8
16
16
% S
% Thr:
0
8
0
8
8
0
8
8
0
0
0
0
0
8
8
% T
% Val:
8
0
0
16
0
0
8
0
16
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _