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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
3.94
Human Site:
S43
Identified Species:
7.22
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S43
C
G
P
R
R
S
S
S
A
S
P
Q
E
Q
D
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
T31
R
P
P
S
E
E
G
T
F
G
G
F
C
S
S
Rat
Rattus norvegicus
NP_001100236
1203
135799
P31
R
P
A
S
E
E
G
P
L
S
G
L
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
L36
Y
G
E
D
R
G
L
L
M
D
A
Q
Q
W
S
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
D48
N
G
E
R
Q
I
Q
D
K
T
W
A
T
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
T78
T
T
T
T
R
T
Q
T
T
T
P
T
Q
T
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
Maize
Zea mays
NP_001104931
975
110846
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
D33
K
L
F
K
P
S
P
D
S
T
S
T
I
L
I
Red Bread Mold
Neurospora crassa
P38671
1423
159642
S31
R
V
L
P
R
C
S
S
S
L
G
I
R
G
S
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
20
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
26.6
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
0
N.A.
0
6.6
20
P-Site Similarity:
0
0
N.A.
0
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
0
16
0
8
0
0
0
0
16
% D
% Glu:
0
0
16
0
16
16
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
24
0
0
0
8
16
0
0
8
24
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
8
8
8
% I
% Lys:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
0
8
8
8
8
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
16
8
8
0
8
8
0
0
16
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
16
0
0
0
0
16
16
8
0
% Q
% Arg:
24
0
0
16
31
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
16
0
16
16
16
16
16
8
0
0
16
31
% S
% Thr:
8
8
8
8
0
8
0
16
8
24
0
16
8
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _