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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
21.82
Human Site:
S774
Identified Species:
40
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S774
K
V
A
R
E
M
H
S
L
R
A
E
A
L
Y
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
W619
L
G
P
H
G
L
D
W
L
K
I
H
L
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
S745
K
V
A
R
E
M
H
S
L
R
S
E
A
L
Y
Rat
Rattus norvegicus
NP_001100236
1203
135799
S743
K
A
A
R
E
M
H
S
L
R
S
E
A
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
S774
K
K
S
S
E
M
H
S
L
R
M
D
A
L
Y
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
S820
K
V
V
A
E
M
H
S
L
R
M
D
A
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
S905
R
K
Q
A
E
M
Y
S
L
W
C
D
A
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
G472
H
P
Y
L
N
H
L
G
S
D
V
C
R
G
I
Maize
Zea mays
NP_001104931
975
110846
G570
H
P
Y
L
N
H
L
G
S
D
L
C
R
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
G606
P
P
H
L
N
H
L
G
S
D
L
C
R
G
V
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
S798
N
K
F
S
S
D
R
S
N
R
C
D
T
N
Y
Red Bread Mold
Neurospora crassa
P38671
1423
159642
S754
N
E
R
S
G
L
H
S
Q
R
C
F
M
N
F
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
66.6
73.3
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
26.6
N.A.
100
93.3
N.A.
N.A.
N.A.
80
80
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
0
N.A.
0
20
20
P-Site Similarity:
0
0
N.A.
0
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
16
0
0
0
0
0
0
8
0
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
24
24
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
24
0
31
0
0
0
% D
% Glu:
0
8
0
0
47
0
0
0
0
0
0
24
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
0
8
0
0
16
0
0
24
0
0
0
0
0
24
0
% G
% His:
16
0
8
8
0
24
47
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
39
24
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
24
0
16
24
0
54
0
16
0
8
47
0
% L
% Met:
0
0
0
0
0
47
0
0
0
0
16
0
8
0
0
% M
% Asn:
16
0
0
0
24
0
0
0
8
0
0
0
0
16
8
% N
% Pro:
8
24
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
24
0
0
8
0
0
54
0
0
24
0
0
% R
% Ser:
0
0
8
24
8
0
0
62
24
0
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
24
8
0
0
0
0
0
0
0
8
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _