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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLRMT All Species: 24.85
Human Site: S915 Identified Species: 45.56
UniProt: O00411 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00411 NP_005026.3 1230 138620 S915 S D P A A Y V S H L P V H Q D
Chimpanzee Pan troglodytes XP_001172601 311 35421 A14 G L Q Q H Y A A L G R D S V G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542220 1024 113870 G727 L Q H Y A A L G R D S I G A A
Cat Felis silvestris
Mouse Mus musculus Q8BKF1 1207 136686 S886 P D P A A Y I S H L P V H Q D
Rat Rattus norvegicus NP_001100236 1203 135799 S884 P D P T A Y V S H L P V H Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080987 1235 142073 S915 P D P T K Y I S H F P V H Q D
Zebra Danio Brachydanio rerio XP_685138 1253 143135 S953 E I A N A S R S P D H H K F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608565 1369 156753 S1046 P D P A A Y L S R F P I H Q D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311418 877 99587 S580 T P V H Q D G S C N G L Q H Y
Maize Zea mays NP_001104931 975 110846 S678 I P V H Q D G S C N G L Q H Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFV6 1011 114502 S714 I P I H Q D G S C N G L Q H Y
Baker's Yeast Sacchar. cerevisiae P13433 1351 153063 S938 D N P E E F I S H Q P V H Q D
Red Bread Mold Neurospora crassa P38671 1423 159642 S894 E D P T K Y V S H L P I H Q D
Conservation
Percent
Protein Identity: 100 23.4 N.A. 59.1 N.A. 66.9 65.6 N.A. N.A. N.A. 47.8 45.5 N.A. 37 N.A. N.A. N.A.
Protein Similarity: 100 24.2 N.A. 67.7 N.A. 78.2 77.9 N.A. N.A. N.A. 65 63.6 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 86.6 86.6 N.A. N.A. N.A. 66.6 13.3 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 N.A. 20 N.A. 93.3 86.6 N.A. N.A. N.A. 73.3 13.3 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: 30.7 30.8 N.A. 30 26.8 26.2
Protein Similarity: 44.1 46.9 N.A. 47.5 44.5 41.5
P-Site Identity: 6.6 6.6 N.A. 6.6 53.3 73.3
P-Site Similarity: 20 13.3 N.A. 13.3 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 24 47 8 8 8 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % C
% Asp: 8 47 0 0 0 24 0 0 0 16 0 8 0 0 54 % D
% Glu: 16 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 16 0 0 0 8 0 % F
% Gly: 8 0 0 0 0 0 24 8 0 8 24 0 8 0 8 % G
% His: 0 0 8 24 8 0 0 0 47 0 8 8 54 24 0 % H
% Ile: 16 8 8 0 0 0 24 0 0 0 0 24 0 0 8 % I
% Lys: 0 0 0 0 16 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 8 0 0 0 0 16 0 8 31 0 24 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 24 0 0 0 0 0 % N
% Pro: 31 24 54 0 0 0 0 0 8 0 54 0 0 0 0 % P
% Gln: 0 8 8 8 24 0 0 0 0 8 0 0 24 54 0 % Q
% Arg: 0 0 0 0 0 0 8 0 16 0 8 0 0 0 0 % R
% Ser: 8 0 0 0 0 8 0 85 0 0 8 0 8 0 0 % S
% Thr: 8 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 16 0 0 0 24 0 0 0 0 39 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 54 0 0 0 0 0 0 0 0 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _