KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
15.45
Human Site:
S949
Identified Species:
28.33
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
S949
A
S
V
N
L
E
P
S
D
V
P
Q
D
V
Y
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
R48
A
A
Q
V
E
V
F
R
R
E
D
A
Q
R
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
Q761
Q
V
E
V
F
R
R
Q
D
A
Q
R
G
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
S920
A
S
V
N
L
T
P
S
D
L
P
Q
D
V
Y
Rat
Rattus norvegicus
NP_001100236
1203
135799
S918
A
S
V
N
L
T
P
S
D
L
P
Q
D
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
C949
K
S
V
N
L
M
P
C
D
T
P
Q
D
V
Y
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
A987
L
G
R
D
V
I
G
A
T
S
V
N
L
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
S1080
R
S
V
N
L
A
P
S
A
I
P
Q
D
V
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
G614
K
P
A
D
V
Y
S
G
I
A
T
R
V
L
D
Maize
Zea mays
NP_001104931
975
110846
G712
K
P
A
D
V
Y
T
G
I
A
N
R
V
M
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
G748
K
P
A
D
V
Y
S
G
I
A
T
R
V
L
D
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
S972
T
Q
V
N
L
V
P
S
D
K
P
Q
D
V
Y
Red Bread Mold
Neurospora crassa
P38671
1423
159642
G928
Q
Q
V
N
L
V
P
G
D
R
P
A
D
V
Y
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
73.3
0
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
20
N.A.
93.3
93.3
N.A.
N.A.
N.A.
73.3
26.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
0
N.A.
0
73.3
60
P-Site Similarity:
26.6
26.6
N.A.
26.6
73.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
24
0
0
8
0
8
8
31
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
0
0
0
54
0
8
0
54
0
16
% D
% Glu:
0
0
8
0
8
8
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
31
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
24
8
0
0
0
0
0
% I
% Lys:
31
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
54
0
0
0
0
16
0
0
8
16
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
54
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
24
0
0
0
0
54
0
0
0
54
0
0
0
8
% P
% Gln:
16
16
8
0
0
0
0
8
0
0
8
47
8
0
0
% Q
% Arg:
8
0
8
0
0
8
8
8
8
8
0
31
0
8
8
% R
% Ser:
0
39
0
0
0
0
16
39
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
16
8
0
8
8
16
0
0
0
0
% T
% Val:
0
8
54
16
31
24
0
0
0
8
8
0
24
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _