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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
12.73
Human Site:
T315
Identified Species:
23.33
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
T315
R
Q
D
Q
D
A
G
T
I
E
R
C
L
E
Q
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
E227
T
L
K
Q
L
R
T
E
W
A
Q
A
L
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
T287
R
R
D
Q
D
V
R
T
I
Q
R
C
L
K
Q
Rat
Rattus norvegicus
NP_001100236
1203
135799
T285
R
R
D
Q
D
A
H
T
I
Q
R
C
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
K310
G
R
S
D
T
A
T
K
S
I
E
M
C
L
S
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
V353
M
Q
N
C
E
T
V
V
I
A
R
C
L
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
Y412
P
D
E
E
N
H
Q
Y
I
S
E
Y
V
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
F80
K
S
L
F
L
G
W
F
E
P
L
R
D
A
I
Maize
Zea mays
NP_001104931
975
110846
S178
P
N
L
P
Y
V
K
S
L
F
L
G
W
F
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
Y214
K
L
A
P
N
L
P
Y
V
K
S
L
F
L
G
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
S317
L
D
P
L
R
E
V
S
F
H
G
S
T
E
V
Red Bread Mold
Neurospora crassa
P38671
1423
159642
Q293
Q
Q
Q
Q
Q
Q
E
Q
Q
Q
Q
Q
D
T
S
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
13.3
N.A.
66.6
73.3
N.A.
N.A.
N.A.
6.6
40
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
20
N.A.
86.6
93.3
N.A.
N.A.
N.A.
13.3
60
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
0
N.A.
0
6.6
13.3
P-Site Similarity:
6.6
20
N.A.
26.6
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
24
0
0
0
16
0
8
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
31
8
8
0
% C
% Asp:
0
16
24
8
24
0
0
0
0
0
0
0
16
0
0
% D
% Glu:
0
0
8
8
8
8
8
8
8
8
16
0
0
16
8
% E
% Phe:
0
0
0
8
0
0
0
8
8
8
0
0
8
8
0
% F
% Gly:
8
0
0
0
0
8
8
0
0
0
8
8
0
0
8
% G
% His:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
39
8
0
0
0
0
8
% I
% Lys:
16
0
8
0
0
0
8
8
0
8
0
0
0
16
8
% K
% Leu:
8
16
16
8
16
8
0
0
8
0
16
8
39
16
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
8
0
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
8
16
0
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
8
24
8
39
8
8
8
8
8
24
16
8
0
8
31
% Q
% Arg:
24
24
0
0
8
8
8
0
0
0
31
8
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
16
8
8
8
8
0
8
16
% S
% Thr:
8
0
0
0
8
8
16
24
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
0
16
16
8
8
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
8
0
0
16
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _