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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
1.82
Human Site:
T346
Identified Species:
3.33
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
T346
L
S
E
E
D
R
A
T
V
L
K
A
V
H
K
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
L258
R
P
S
L
F
P
F
L
C
V
L
T
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
A318
L
E
E
E
D
R
A
A
L
L
R
A
V
V
K
Rat
Rattus norvegicus
NP_001100236
1203
135799
A316
L
E
E
E
D
R
A
A
L
L
R
A
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
D341
L
Y
K
E
D
E
R
D
M
I
L
K
A
V
R
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
M384
F
K
K
D
E
R
E
M
V
L
R
A
V
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
I443
F
V
A
D
Q
R
D
I
A
L
D
A
I
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
A111
A
H
F
S
D
L
P
A
D
M
M
A
V
I
T
Maize
Zea mays
NP_001104931
975
110846
P209
G
S
R
A
S
H
G
P
F
F
S
M
L
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
T245
R
L
G
K
S
K
A
T
Y
A
H
Y
L
D
Q
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
L348
R
V
I
R
H
T
L
L
G
L
S
L
T
P
E
Red Bread Mold
Neurospora crassa
P38671
1423
159642
L324
P
S
A
I
P
E
V
L
G
T
P
Q
K
G
F
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
0
N.A.
66.6
66.6
N.A.
N.A.
N.A.
20
33.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
13.3
N.A.
80
80
N.A.
N.A.
N.A.
46.6
60
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
20
6.6
N.A.
13.3
6.6
6.6
P-Site Similarity:
26.6
13.3
N.A.
40
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
0
31
24
8
8
0
47
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
39
0
8
8
8
0
8
0
0
8
0
% D
% Glu:
0
16
24
31
8
16
8
0
0
0
0
0
8
8
16
% E
% Phe:
16
0
8
0
8
0
8
0
8
8
0
0
0
0
8
% F
% Gly:
8
0
8
0
0
0
8
0
16
0
0
0
0
8
0
% G
% His:
0
8
0
0
8
8
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
8
8
0
0
0
8
0
8
0
0
8
8
0
% I
% Lys:
0
8
16
8
0
8
0
0
0
0
8
8
8
0
24
% K
% Leu:
31
8
0
8
0
8
8
24
16
47
16
8
16
0
8
% L
% Met:
0
0
0
0
0
0
0
8
8
8
8
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
8
8
8
8
0
0
8
0
0
16
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
8
% Q
% Arg:
24
0
8
8
0
39
8
0
0
0
24
0
0
8
16
% R
% Ser:
0
24
8
8
16
0
0
0
0
0
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
16
0
8
0
8
8
0
8
% T
% Val:
0
16
0
0
0
0
8
0
16
8
0
0
39
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _