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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
18.48
Human Site:
T993
Identified Species:
33.89
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
T993
T
R
K
V
V
K
Q
T
V
M
T
V
V
Y
G
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
V78
V
K
Q
T
V
M
T
V
V
Y
G
V
T
R
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
Y791
Q
T
V
M
T
V
V
Y
G
V
T
R
Y
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
T964
S
R
K
V
V
K
Q
T
V
M
T
V
V
Y
G
Rat
Rattus norvegicus
NP_001100236
1203
135799
T962
S
R
K
V
V
K
Q
T
V
M
T
V
V
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
T993
G
R
K
V
V
K
Q
T
V
M
T
V
V
Y
G
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
R1019
F
R
V
R
D
A
E
R
G
L
K
I
A
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
T1124
R
R
K
V
I
K
Q
T
V
M
T
T
V
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
V644
S
V
H
A
K
L
L
V
N
Q
V
D
R
K
L
Maize
Zea mays
NP_001104931
975
110846
V742
A
A
R
A
R
L
I
V
D
Q
V
D
R
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
L778
A
L
R
A
R
K
L
L
N
Q
V
D
R
K
L
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
F1031
V
T
Y
V
G
A
T
F
Q
I
A
K
Q
L
S
Red Bread Mold
Neurospora crassa
P38671
1423
159642
A1022
V
T
Q
H
I
F
R
A
M
S
T
M
F
K
G
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
20
N.A.
13.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
6.6
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
26.6
N.A.
100
100
N.A.
N.A.
N.A.
93.3
26.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
0
0
N.A.
6.6
6.6
13.3
P-Site Similarity:
6.6
6.6
N.A.
13.3
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
24
0
16
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
24
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
16
0
8
0
0
8
54
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
8
0
0
8
0
8
0
0
0
% I
% Lys:
0
8
39
0
8
47
0
0
0
0
8
8
0
31
0
% K
% Leu:
0
8
0
0
0
16
16
8
0
8
0
0
0
8
24
% L
% Met:
0
0
0
8
0
8
0
0
8
39
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
0
39
0
8
24
0
0
8
8
0
% Q
% Arg:
8
47
16
8
16
0
8
8
0
0
0
8
24
8
0
% R
% Ser:
24
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% S
% Thr:
8
24
0
8
8
0
16
39
0
0
54
8
8
0
0
% T
% Val:
24
8
16
47
39
8
8
24
47
8
24
39
39
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
8
0
0
8
39
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _