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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLRMT
All Species:
13.33
Human Site:
Y533
Identified Species:
24.44
UniProt:
O00411
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00411
NP_005026.3
1230
138620
Y533
L
Q
N
H
Y
R
K
Y
L
C
L
L
A
S
D
Chimpanzee
Pan troglodytes
XP_001172601
311
35421
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542220
1024
113870
P431
E
V
P
M
L
C
P
P
L
P
W
T
S
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKF1
1207
136686
Y505
L
G
Q
R
Y
S
Q
Y
L
Q
L
L
A
S
D
Rat
Rattus norvegicus
NP_001100236
1203
135799
Y503
L
G
Q
Q
Y
S
Q
Y
L
R
L
L
A
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080987
1235
142073
Y529
I
K
V
L
Y
R
D
Y
C
Q
L
L
A
K
N
Zebra Danio
Brachydanio rerio
XP_685138
1253
143135
Y572
L
R
S
I
Y
S
S
Y
A
E
L
L
A
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608565
1369
156753
Y649
I
G
E
I
Y
S
S
Y
C
E
L
W
G
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311418
877
99587
I284
S
S
R
R
Y
G
V
I
E
C
D
P
L
V
R
Maize
Zea mays
NP_001104931
975
110846
I382
S
S
R
R
Y
G
V
I
K
C
D
P
L
V
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFV6
1011
114502
I418
S
G
R
K
Y
G
V
I
E
C
D
P
L
V
R
Baker's Yeast
Sacchar. cerevisiae
P13433
1351
153063
E549
I
E
M
E
F
R
S
E
Q
V
L
K
S
E
S
Red Bread Mold
Neurospora crassa
P38671
1423
159642
V518
K
Q
H
N
P
R
S
V
L
R
F
K
N
S
T
Conservation
Percent
Protein Identity:
100
23.4
N.A.
59.1
N.A.
66.9
65.6
N.A.
N.A.
N.A.
47.8
45.5
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
N.A.
67.7
N.A.
78.2
77.9
N.A.
N.A.
N.A.
65
63.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
60
60
N.A.
N.A.
N.A.
40
46.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
13.3
N.A.
66.6
66.6
N.A.
N.A.
N.A.
60
66.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
30.7
30.8
N.A.
30
26.8
26.2
Protein Similarity:
44.1
46.9
N.A.
47.5
44.5
41.5
P-Site Identity:
13.3
13.3
N.A.
13.3
13.3
26.6
P-Site Similarity:
13.3
13.3
N.A.
13.3
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
39
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
16
31
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
24
0
0
0
31
% D
% Glu:
8
8
8
8
0
0
0
8
16
16
0
0
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
31
0
0
0
24
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
24
0
0
16
0
0
0
24
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
8
0
0
8
0
8
0
0
16
0
8
0
% K
% Leu:
31
0
0
8
8
0
0
0
39
0
54
39
24
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
8
8
8
% N
% Pro:
0
0
8
0
8
0
8
8
0
8
0
24
0
8
0
% P
% Gln:
0
16
16
8
0
0
16
0
8
16
0
0
0
0
0
% Q
% Arg:
0
8
24
24
0
31
0
0
0
16
0
0
0
0
24
% R
% Ser:
24
16
8
0
0
31
31
0
0
0
0
0
16
39
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
0
8
8
0
0
0
24
8
0
8
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
0
0
0
0
70
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _