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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLRMT All Species: 20.61
Human Site: Y956 Identified Species: 37.78
UniProt: O00411 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00411 NP_005026.3 1230 138620 Y956 S D V P Q D V Y S G V A A Q V
Chimpanzee Pan troglodytes XP_001172601 311 35421 G55 R R E D A Q R G M R V A Q V L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542220 1024 113870 R768 Q D A Q R G V R V A Q V L E G
Cat Felis silvestris
Mouse Mus musculus Q8BKF1 1207 136686 Y927 S D L P Q D V Y R E V A T Q V
Rat Rattus norvegicus NP_001100236 1203 135799 Y925 S D L P Q D V Y R E V A T Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080987 1235 142073 Y956 C D T P Q D V Y S G V A Q Q V
Zebra Danio Brachydanio rerio XP_685138 1253 143135 P994 A T S V N L M P C A L P Q D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608565 1369 156753 Y1087 S A I P Q D V Y S A V A A L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311418 877 99587 D621 G I A T R V L D I M Q R D A E
Maize Zea mays NP_001104931 975 110846 E719 G I A N R V M E I M R M D A Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFV6 1011 114502 D755 G I A T R V L D I M R R D A D
Baker's Yeast Sacchar. cerevisiae P13433 1351 153063 Y979 S D K P Q D V Y A H V A R L V
Red Bread Mold Neurospora crassa P38671 1423 159642 Y935 G D R P A D V Y S A V A K L V
Conservation
Percent
Protein Identity: 100 23.4 N.A. 59.1 N.A. 66.9 65.6 N.A. N.A. N.A. 47.8 45.5 N.A. 37 N.A. N.A. N.A.
Protein Similarity: 100 24.2 N.A. 67.7 N.A. 78.2 77.9 N.A. N.A. N.A. 65 63.6 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 13.3 N.A. 13.3 N.A. 73.3 73.3 N.A. N.A. N.A. 80 6.6 N.A. 73.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 26.6 N.A. 80 80 N.A. N.A. N.A. 80 26.6 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: 30.7 30.8 N.A. 30 26.8 26.2
Protein Similarity: 44.1 46.9 N.A. 47.5 44.5 41.5
P-Site Identity: 0 0 N.A. 0 66.6 60
P-Site Similarity: 13.3 13.3 N.A. 13.3 73.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 31 0 16 0 0 0 8 31 0 62 16 24 0 % A
% Cys: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 54 0 8 0 54 0 16 0 0 0 0 24 8 8 % D
% Glu: 0 0 8 0 0 0 0 8 0 16 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 31 0 0 0 0 8 0 8 0 16 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 24 8 0 0 0 0 0 24 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 16 0 0 8 16 0 0 0 8 0 8 24 8 % L
% Met: 0 0 0 0 0 0 16 0 8 24 0 8 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 54 0 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 8 0 0 8 47 8 0 0 0 0 16 0 24 31 8 % Q
% Arg: 8 8 8 0 31 0 8 8 16 8 16 16 8 0 0 % R
% Ser: 39 0 8 0 0 0 0 0 31 0 0 0 0 0 0 % S
% Thr: 0 8 8 16 0 0 0 0 0 0 0 0 16 0 0 % T
% Val: 0 0 8 8 0 24 62 0 8 0 62 8 0 8 62 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _