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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
7.27
Human Site:
S115
Identified Species:
13.33
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
S115
T
G
S
L
P
S
P
S
G
V
R
K
E
T
A
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
S115
K
S
N
I
K
R
T
S
S
S
E
R
V
S
P
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
K114
E
T
A
V
P
T
T
K
S
N
I
K
R
T
S
Dog
Lupus familis
XP_547975
846
93085
S146
K
R
L
H
R
S
A
S
L
L
A
A
C
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
P114
P
S
A
S
L
P
A
P
S
G
A
R
K
E
V
Rat
Rattus norvegicus
Q4V8C3
814
89783
P114
P
S
A
S
L
P
S
P
S
G
S
R
K
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
N160
K
R
L
N
R
S
V
N
L
L
S
A
C
K
L
Chicken
Gallus gallus
XP_421362
815
90017
S115
S
G
S
L
P
S
P
S
G
T
R
K
E
T
V
Frog
Xenopus laevis
Q2TAF3
927
102313
R114
S
A
A
K
S
V
K
R
S
S
T
L
E
K
S
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
S114
R
L
S
G
F
P
S
S
P
S
S
P
K
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
L371
A
D
V
D
T
F
Y
L
A
T
G
T
A
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
D174
V
S
T
H
D
M
K
D
T
D
R
F
R
R
L
Sea Urchin
Strong. purpuratus
Q26613
686
75435
A8
M
S
N
R
P
S
T
A
R
P
N
S
A
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
6.6
20
13.3
N.A.
0
0
N.A.
6.6
80
6.6
13.3
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
33.3
46.6
20
N.A.
20
20
N.A.
20
86.6
26.6
20
N.A.
0
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
31
0
0
0
16
8
8
0
16
16
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% C
% Asp:
0
8
0
8
8
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
8
0
24
16
8
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
16
0
8
0
0
0
0
16
16
8
0
0
0
0
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
24
0
0
8
8
0
16
8
0
0
0
24
24
24
0
% K
% Leu:
0
8
16
16
16
0
0
8
16
16
0
8
0
8
24
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
16
8
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
16
0
0
0
31
24
16
16
8
8
0
8
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
0
8
16
8
0
8
8
0
24
24
16
16
0
% R
% Ser:
16
39
24
16
8
39
16
39
39
24
24
8
0
16
16
% S
% Thr:
8
8
8
0
8
8
24
0
8
16
8
8
0
24
0
% T
% Val:
8
0
8
8
0
8
8
0
0
8
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _