KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
26.36
Human Site:
S151
Identified Species:
48.33
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
S151
R
R
E
S
N
G
D
S
R
G
N
R
N
R
T
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
N151
S
S
S
S
G
K
K
N
S
E
S
K
P
K
E
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
S150
N
R
T
G
S
T
S
S
S
S
S
G
K
K
N
Dog
Lupus familis
XP_547975
846
93085
S182
R
R
E
S
Y
G
D
S
K
G
N
R
N
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
S150
R
R
E
S
S
G
D
S
K
G
S
R
N
R
T
Rat
Rattus norvegicus
Q4V8C3
814
89783
S150
R
R
E
S
S
G
D
S
K
G
S
R
N
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
S196
R
K
E
S
Y
G
D
S
K
G
S
R
N
R
T
Chicken
Gallus gallus
XP_421362
815
90017
S151
R
R
E
S
Y
G
D
S
K
G
S
R
N
R
T
Frog
Xenopus laevis
Q2TAF3
927
102313
K150
K
L
T
S
K
V
S
K
A
T
D
K
H
K
D
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
T150
M
A
D
S
R
S
R
T
T
S
S
S
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
V407
P
T
D
E
L
P
K
V
P
L
R
G
A
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
S210
L
S
T
T
H
R
Q
S
S
P
S
L
L
S
L
Sea Urchin
Strong. purpuratus
Q26613
686
75435
G44
S
P
R
G
G
S
A
G
G
K
R
F
S
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
6.6
13.3
86.6
N.A.
80
80
N.A.
73.3
80
6.6
13.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
33.3
33.3
93.3
N.A.
100
100
N.A.
93.3
93.3
40
40
N.A.
13.3
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
47
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
47
8
0
0
0
0
0
8
0
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
16
16
47
0
8
8
47
0
16
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
8
8
16
8
39
8
0
16
8
31
0
% K
% Leu:
8
8
0
0
8
0
0
0
0
8
0
8
8
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
0
0
16
0
47
0
8
% N
% Pro:
8
8
0
0
0
8
0
0
8
8
0
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
47
47
8
0
8
8
8
0
8
0
16
47
0
54
0
% R
% Ser:
16
16
8
70
24
16
16
62
24
16
62
8
16
16
0
% S
% Thr:
0
8
24
8
0
8
0
8
8
8
0
0
0
0
54
% T
% Val:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _