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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
27.88
Human Site:
S452
Identified Species:
51.11
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
S452
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
G443
V
Q
G
A
H
E
G
G
I
F
A
L
C
M
L
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
Q443
N
R
I
S
Y
A
V
Q
G
A
H
E
G
G
I
Dog
Lupus familis
XP_547975
846
93085
S483
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
S451
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Rat
Rattus norvegicus
Q4V8C3
814
89783
S451
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
S497
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Chicken
Gallus gallus
XP_421362
815
90017
S452
G
K
G
T
N
R
I
S
H
A
V
Q
G
A
H
Frog
Xenopus laevis
Q2TAF3
927
102313
I447
V
Y
Q
I
S
K
Q
I
K
A
H
D
G
S
V
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
S442
A
K
G
G
N
R
I
S
K
V
V
S
G
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
Y704
S
V
D
S
D
G
A
Y
F
V
R
T
E
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
T535
D
P
R
T
C
K
T
T
K
Q
A
H
S
V
H
Sea Urchin
Strong. purpuratus
Q26613
686
75435
F335
G
A
H
E
G
G
I
F
S
L
C
V
M
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
100
93.3
13.3
66.6
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
20
40
100
N.A.
100
100
N.A.
100
100
33.3
66.6
N.A.
20
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
0
0
62
16
0
0
54
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% C
% Asp:
8
0
8
0
8
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% F
% Gly:
54
0
62
8
8
16
8
8
8
0
0
0
70
8
0
% G
% His:
0
0
8
0
8
0
0
0
8
0
16
8
0
0
62
% H
% Ile:
0
0
8
8
0
0
62
8
8
0
0
0
0
0
8
% I
% Lys:
0
54
0
0
0
16
0
0
24
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
8
0
0
0
54
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
8
8
0
8
0
47
0
0
0
% Q
% Arg:
0
8
8
0
0
54
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
16
8
0
0
54
8
0
0
8
8
8
0
% S
% Thr:
0
0
0
54
0
0
8
8
0
0
0
8
0
0
0
% T
% Val:
16
8
0
0
0
0
8
0
0
16
54
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
8
39
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _