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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
4.55
Human Site:
S488
Identified Species:
8.33
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
S488
D
R
K
L
I
S
W
S
G
N
Y
Q
K
L
R
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
K474
S
W
S
G
N
Y
Q
K
L
H
K
T
E
I
P
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
S475
D
R
K
L
I
S
W
S
G
N
Y
Q
K
L
R
Dog
Lupus familis
XP_547975
846
93085
N519
D
R
K
L
I
S
W
N
G
N
Y
Q
K
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
N487
D
R
R
L
I
S
W
N
G
N
Y
Q
K
L
H
Rat
Rattus norvegicus
Q4V8C3
814
89783
N487
D
R
R
L
I
S
W
N
G
N
Y
Q
K
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
N533
D
R
K
L
I
S
W
N
G
N
Y
Q
K
L
H
Chicken
Gallus gallus
XP_421362
815
90017
N488
D
R
K
L
I
S
W
N
G
N
Y
Q
K
L
H
Frog
Xenopus laevis
Q2TAF3
927
102313
D479
D
R
K
V
I
M
W
D
H
D
L
N
P
E
R
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
D478
D
R
K
V
L
L
W
D
H
D
Y
R
K
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
K748
W
D
S
L
Q
N
Y
K
K
I
A
D
T
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
L571
R
M
V
S
E
W
D
L
Q
D
L
V
R
T
R
Sea Urchin
Strong. purpuratus
Q26613
686
75435
E366
T
A
D
Y
Q
Q
S
E
V
T
Q
V
T
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
0
100
93.3
N.A.
80
80
N.A.
86.6
86.6
40
40
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
53.3
66.6
N.A.
20
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
8
8
0
0
0
8
16
0
24
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
8
0
0
0
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
54
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
31
% H
% Ile:
0
0
0
0
62
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
54
0
0
0
0
16
8
0
8
0
62
16
0
% K
% Leu:
0
0
0
62
8
8
0
8
8
0
16
0
0
54
8
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
39
0
54
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
16
8
8
0
8
0
8
54
0
0
0
% Q
% Arg:
8
70
16
0
0
0
0
0
0
0
0
8
8
0
39
% R
% Ser:
8
0
16
8
0
54
8
16
0
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
8
16
8
0
% T
% Val:
0
0
8
16
0
0
0
0
8
0
0
16
0
0
0
% V
% Trp:
8
8
0
0
0
8
70
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _