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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EML1 All Species: 21.52
Human Site: T133 Identified Species: 39.44
UniProt: O00423 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00423 NP_001008707.1 815 89861 T133 T K S N I K R T S S S E R V S
Chimpanzee Pan troglodytes XP_001157625 796 87796 R133 R E S N G D S R G N R N R T G
Rhesus Macaque Macaca mulatta XP_001103968 802 88141 R132 R V S P G G R R E S N G D S K
Dog Lupus familis XP_547975 846 93085 T164 A H S T I K R T S S S E R V S
Cat Felis silvestris
Mouse Mus musculus Q05BC3 814 89661 T132 V T K S I N R T S S S E R V S
Rat Rattus norvegicus Q4V8C3 814 89783 T132 V T K S I N R T S S S E R V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512831 860 95042 T178 A P S T I K R T S S T E R V S
Chicken Gallus gallus XP_421362 815 90017 T133 A K S T V K R T S S A E R V S
Frog Xenopus laevis Q2TAF3 927 102313 R132 W D A S E E S R N K L M R A A
Zebra Danio Brachydanio rerio NP_001025406 805 88511 S132 S I K R K S M S T E R L S T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUI3 1076 119237 R389 P I R R S R S R P S V V A A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45487 891 98353 T192 S E A S T S A T M N P I V N S
Sea Urchin Strong. purpuratus Q26613 686 75435 S26 N T P G R P S S A R P G S G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 96.9 91.3 N.A. 96.1 96.3 N.A. 87.4 92.8 49.6 65.6 N.A. 29.6 N.A. 26.9 50.6
Protein Similarity: 100 97.4 97.3 93.7 N.A. 97.9 98.1 N.A. 91.8 97.4 64.9 81.3 N.A. 45.4 N.A. 48.7 65.6
P-Site Identity: 100 20 20 80 N.A. 66.6 66.6 N.A. 73.3 73.3 6.6 0 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 33.3 26.6 80 N.A. 73.3 73.3 N.A. 80 86.6 40 20 N.A. 20 N.A. 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 16 0 0 0 8 0 8 0 8 0 8 16 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 16 0 0 8 8 0 0 8 8 0 47 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 16 8 0 0 8 0 0 16 0 8 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 39 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 16 24 0 8 31 0 0 0 8 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % M
% Asn: 8 0 0 16 0 16 0 0 8 16 8 8 0 8 0 % N
% Pro: 8 8 8 8 0 8 0 0 8 0 16 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 0 8 16 8 8 54 31 0 8 16 0 62 0 8 % R
% Ser: 16 0 47 31 8 16 31 16 47 62 31 0 16 8 54 % S
% Thr: 8 24 0 24 8 0 0 54 8 0 8 0 0 16 0 % T
% Val: 16 8 0 0 8 0 0 0 0 0 8 8 8 47 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _