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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EML1 All Species: 23.64
Human Site: T161 Identified Species: 43.33
UniProt: O00423 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00423 NP_001008707.1 815 89861 T161 N R N R T G S T S S S S S G K
Chimpanzee Pan troglodytes XP_001157625 796 87796 F161 S K P K E P V F S A E E G Y V
Rhesus Macaque Macaca mulatta XP_001103968 802 88141 S160 S G K K N S E S K P K E P V F
Dog Lupus familis XP_547975 846 93085 T192 N R N R T G S T S S S S S G K
Cat Felis silvestris
Mouse Mus musculus Q05BC3 814 89661 T160 S R N R T G S T S S S S S G K
Rat Rattus norvegicus Q4V8C3 814 89783 T160 S R N R T G S T S S S S S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512831 860 95042 T206 S R N R T G S T S S S S S G K
Chicken Gallus gallus XP_421362 815 90017 T161 S R N R T G S T S S S S S G K
Frog Xenopus laevis Q2TAF3 927 102313 I160 D K H K D I V I S P E G E Y I
Zebra Danio Brachydanio rerio NP_001025406 805 88511 K160 S S S S T C G K R D S K T K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUI3 1076 119237 K417 R G A R P R S K S R P R I L Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45487 891 98353 V220 S L L S L C S V I S R S P S T
Sea Urchin Strong. purpuratus Q26613 686 75435 H54 R F S K E P Q H N A E E G Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 96.9 91.3 N.A. 96.1 96.3 N.A. 87.4 92.8 49.6 65.6 N.A. 29.6 N.A. 26.9 50.6
Protein Similarity: 100 97.4 97.3 93.7 N.A. 97.9 98.1 N.A. 91.8 97.4 64.9 81.3 N.A. 45.4 N.A. 48.7 65.6
P-Site Identity: 100 6.6 0 100 N.A. 93.3 93.3 N.A. 93.3 93.3 6.6 13.3 N.A. 20 N.A. 20 0
P-Site Similarity: 100 33.3 20 100 N.A. 100 100 N.A. 100 100 33.3 40 N.A. 20 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 16 0 8 0 0 0 24 24 8 0 8 % E
% Phe: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 0 16 0 0 0 47 8 0 0 0 0 8 16 47 0 % G
% His: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 8 8 0 0 0 8 0 8 % I
% Lys: 0 16 8 31 0 0 0 16 8 0 8 8 0 8 47 % K
% Leu: 0 8 8 0 8 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 47 0 8 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 8 16 0 0 0 16 8 0 16 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 16 47 0 54 0 8 0 0 8 8 8 8 0 0 0 % R
% Ser: 62 8 16 16 0 8 62 8 70 54 54 54 47 8 0 % S
% Thr: 0 0 0 0 54 0 0 47 0 0 0 0 8 0 8 % T
% Val: 0 0 0 0 0 0 16 8 0 0 0 0 0 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _