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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
35.45
Human Site:
T613
Identified Species:
65
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
T613
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
T594
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
T600
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Dog
Lupus familis
XP_547975
846
93085
T644
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
T612
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Rat
Rattus norvegicus
Q4V8C3
814
89783
T612
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
T658
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Chicken
Gallus gallus
XP_421362
815
90017
T613
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Frog
Xenopus laevis
Q2TAF3
927
102313
A604
G
R
W
F
V
L
D
A
E
T
R
D
L
V
S
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
T603
A
K
W
L
V
L
D
T
D
T
R
D
L
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
N872
L
L
V
I
N
C
E
N
G
A
V
M
L
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
G690
I
I
L
G
F
A
A
G
L
W
I
V
M
N
I
Sea Urchin
Strong. purpuratus
Q26613
686
75435
E485
R
W
V
A
L
D
V
E
S
Q
D
L
I
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
73.3
53.3
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
80
N.A.
13.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
77
0
8
0
8
77
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
8
70
0
0
0
0
0
0
% E
% Phe:
0
0
0
70
8
62
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
8
0
8
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
62
0
0
0
0
% K
% Leu:
8
8
8
8
8
16
0
0
8
0
0
8
85
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
70
0
0
0
0
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
16
% S
% Thr:
0
0
0
0
0
0
0
70
0
77
0
0
0
16
62
% T
% Val:
0
0
16
0
77
0
8
0
0
0
8
8
0
77
8
% V
% Trp:
0
8
77
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _