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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
29.09
Human Site:
Y227
Identified Species:
53.33
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
Y227
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
T227
Y
L
L
P
T
G
E
T
V
Y
F
I
A
S
V
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
Y226
R
D
C
R
N
N
L
Y
L
L
P
T
G
E
T
Dog
Lupus familis
XP_547975
846
93085
Y258
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
Y226
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Rat
Rattus norvegicus
Q4V8C3
814
89783
Y226
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
Y272
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Chicken
Gallus gallus
XP_421362
815
90017
Y227
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Frog
Xenopus laevis
Q2TAF3
927
102313
Y226
L
P
T
G
E
I
V
Y
F
I
A
S
V
V
V
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
S226
Y
R
G
R
D
C
R
S
N
L
Y
L
L
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
H483
K
L
Q
L
Q
W
V
H
G
Y
R
G
I
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
Y286
K
V
T
L
K
H
V
Y
S
Y
R
G
K
D
V
Sea Urchin
Strong. purpuratus
Q26613
686
75435
I120
L
L
P
T
G
E
I
I
Y
F
M
A
A
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
100
100
20
0
N.A.
60
N.A.
46.6
6.6
P-Site Similarity:
100
13.3
26.6
100
N.A.
100
100
N.A.
100
100
20
6.6
N.A.
86.6
N.A.
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
8
16
0
8
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
47
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
0
62
0
% D
% Glu:
0
0
0
0
54
8
8
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% F
% Gly:
0
0
8
8
8
8
0
0
54
0
0
62
8
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
8
0
8
0
8
8
0
0
% I
% Lys:
16
0
47
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
16
70
8
62
0
0
8
0
8
16
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
8
8
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
54
8
0
16
0
0
8
0
0
0
62
0
47
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% S
% Thr:
0
0
16
8
8
0
0
8
0
0
0
8
0
0
16
% T
% Val:
0
8
0
0
0
0
70
0
8
0
0
0
8
16
31
% V
% Trp:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
70
8
70
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _