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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML1
All Species:
26.36
Human Site:
Y267
Identified Species:
48.33
UniProt:
O00423
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00423
NP_001008707.1
815
89861
Y267
E
E
Q
L
Q
R
H
Y
A
G
H
N
D
D
V
Chimpanzee
Pan troglodytes
XP_001157625
796
87796
I267
V
H
P
D
R
I
T
I
A
T
G
Q
V
A
G
Rhesus Macaque
Macaca mulatta
XP_001103968
802
88141
V266
D
D
V
K
C
L
A
V
H
P
D
R
I
T
I
Dog
Lupus familis
XP_547975
846
93085
Y298
E
E
Q
L
Q
R
H
Y
T
G
H
N
D
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q05BC3
814
89661
Y266
E
E
Q
L
Q
R
H
Y
A
G
H
N
D
D
V
Rat
Rattus norvegicus
Q4V8C3
814
89783
Y266
E
E
Q
L
Q
R
H
Y
A
G
H
N
D
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
Y312
E
E
Q
L
Q
R
H
Y
T
G
H
N
D
D
V
Chicken
Gallus gallus
XP_421362
815
90017
Y267
E
E
Q
L
Q
R
H
Y
T
G
H
N
D
D
V
Frog
Xenopus laevis
Q2TAF3
927
102313
T266
P
D
K
I
R
I
A
T
G
Q
I
A
G
V
D
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
C266
G
H
N
D
D
V
K
C
L
A
I
H
P
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
Y523
D
E
D
A
Q
R
H
Y
T
G
H
T
E
D
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
R326
T
G
E
D
R
S
Q
R
I
Y
H
G
H
T
C
Sea Urchin
Strong. purpuratus
Q26613
686
75435
A160
H
P
D
S
V
T
I
A
T
G
Q
V
A
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.9
91.3
N.A.
96.1
96.3
N.A.
87.4
92.8
49.6
65.6
N.A.
29.6
N.A.
26.9
50.6
Protein Similarity:
100
97.4
97.3
93.7
N.A.
97.9
98.1
N.A.
91.8
97.4
64.9
81.3
N.A.
45.4
N.A.
48.7
65.6
P-Site Identity:
100
6.6
0
93.3
N.A.
100
100
N.A.
93.3
93.3
0
6.6
N.A.
53.3
N.A.
6.6
6.6
P-Site Similarity:
100
13.3
20
93.3
N.A.
100
100
N.A.
93.3
93.3
26.6
20
N.A.
73.3
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
16
8
31
8
0
8
8
8
0
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
16
16
16
24
8
0
0
0
0
0
8
0
47
62
8
% D
% Glu:
47
54
8
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
8
62
8
8
8
8
8
% G
% His:
8
16
0
0
0
0
54
0
8
0
62
8
8
0
8
% H
% Ile:
0
0
0
8
0
16
8
8
8
0
16
0
8
0
16
% I
% Lys:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
47
0
8
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
47
0
0
0
% N
% Pro:
8
8
8
0
0
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
47
0
54
0
8
0
0
8
8
8
0
0
0
% Q
% Arg:
0
0
0
0
24
54
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
8
8
39
8
0
8
0
16
0
% T
% Val:
8
0
8
0
8
8
0
8
0
0
0
8
8
8
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _