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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP3
All Species:
17.88
Human Site:
S243
Identified Species:
43.7
UniProt:
O00425
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00425
NP_006538.2
579
63705
S243
N
A
G
A
A
E
K
S
I
T
I
L
S
T
P
Chimpanzee
Pan troglodytes
XP_001157535
582
64016
S243
N
A
G
A
A
E
K
S
I
T
I
L
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001098422
579
63672
S243
N
A
G
A
A
E
K
S
I
T
I
L
S
T
P
Dog
Lupus familis
XP_539474
579
63750
S243
N
A
G
A
A
E
K
S
I
T
I
L
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPN8
579
63556
S243
N
T
G
A
A
E
K
S
I
T
I
L
S
T
P
Rat
Rattus norvegicus
Q8CGX0
577
63418
A243
N
A
G
A
A
E
K
A
I
S
V
H
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512362
584
64248
P244
N
A
G
A
A
E
K
P
I
T
I
H
S
T
P
Chicken
Gallus gallus
Q5ZLP8
584
64354
P244
N
A
G
A
A
E
K
P
I
T
I
H
S
T
P
Frog
Xenopus laevis
O57526
593
65367
P252
N
A
G
A
A
E
K
P
I
T
I
H
S
T
P
Zebra Danio
Brachydanio rerio
Q9PW80
582
63333
P242
N
A
G
A
A
E
K
P
I
T
V
H
S
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
99.8
98.6
N.A.
96.5
74
N.A.
85.6
85.2
82.4
77.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
100
99.3
N.A.
98.2
84.9
N.A.
92.1
91.6
90.2
86.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
73.3
N.A.
86.6
86.6
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
90
0
100
100
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
100
0
80
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
100
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
10
0
0
100
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
90
0
0
0
100
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _