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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP3
All Species:
16.36
Human Site:
Y397
Identified Species:
40
UniProt:
O00425
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00425
NP_006538.2
579
63705
Y397
P
S
A
M
T
P
P
Y
P
Q
F
E
Q
S
E
Chimpanzee
Pan troglodytes
XP_001157535
582
64016
Y397
P
S
A
M
T
P
P
Y
P
Q
Q
S
F
H
S
Rhesus Macaque
Macaca mulatta
XP_001098422
579
63672
Y397
P
S
A
M
T
P
P
Y
P
Q
F
E
Q
S
E
Dog
Lupus familis
XP_539474
579
63750
Y397
P
S
A
M
T
P
P
Y
P
Q
F
E
Q
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPN8
579
63556
Y397
P
S
T
L
T
P
P
Y
P
Q
F
E
Q
S
E
Rat
Rattus norvegicus
Q8CGX0
577
63418
G397
V
T
G
A
A
P
Y
G
S
F
M
Q
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512362
584
64248
P401
A
A
A
A
T
S
Y
P
P
F
G
Q
Q
P
E
Chicken
Gallus gallus
Q5ZLP8
584
64354
P401
A
A
A
A
A
S
Y
P
P
F
G
Q
Q
P
E
Frog
Xenopus laevis
O57526
593
65367
P409
P
T
T
S
A
S
Y
P
P
F
G
Q
Q
P
E
Zebra Danio
Brachydanio rerio
Q9PW80
582
63333
Q400
P
G
A
Q
A
G
Y
Q
S
F
G
A
Q
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
99.8
98.6
N.A.
96.5
74
N.A.
85.6
85.2
82.4
77.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
100
99.3
N.A.
98.2
84.9
N.A.
92.1
91.6
90.2
86.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
86.6
13.3
N.A.
33.3
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
26.6
N.A.
46.6
40
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
70
30
40
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
90
% E
% Phe:
0
0
0
0
0
0
0
0
0
50
40
0
10
0
0
% F
% Gly:
0
10
10
0
0
10
0
10
0
0
40
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
40
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
0
0
0
0
60
50
30
80
0
0
0
0
40
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
50
10
40
80
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
0
10
0
30
0
0
20
0
0
10
0
40
10
% S
% Thr:
0
20
20
0
60
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _