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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
35.45
Human Site:
S248
Identified Species:
55.71
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
S248
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Chimpanzee
Pan troglodytes
XP_520720
896
98575
S408
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
S248
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Dog
Lupus familis
XP_864886
736
81869
S248
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
S254
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Rat
Rattus norvegicus
O35303
755
83890
S261
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
I241
V
I
P
V
K
L
G
I
I
G
V
V
N
R
S
Frog
Xenopus laevis
NP_001080183
698
77807
S248
I
I
G
V
V
N
R
S
Q
L
D
I
N
N
K
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
G231
D
A
M
D
V
L
M
G
R
V
I
P
V
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
K235
G
V
V
N
R
S
Q
K
D
I
E
G
R
K
D
Honey Bee
Apis mellifera
XP_394947
721
81070
S248
I
I
G
V
V
N
R
S
Q
Q
D
I
M
N
N
Nematode Worm
Caenorhab. elegans
P39055
830
93389
K242
G
V
V
N
R
G
Q
K
D
I
V
G
R
K
D
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
S248
I
I
G
V
V
N
R
S
Q
M
D
I
N
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
E261
G
V
V
N
R
S
Q
E
D
I
L
M
N
R
S
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
Q279
G
V
V
N
R
S
Q
Q
D
I
Q
L
N
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
100
6.6
N.A.
0
80
0
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
100
20
N.A.
33.3
80
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
0
0
27
0
60
0
0
0
14
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
27
0
60
0
0
7
7
7
0
7
0
14
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
67
0
0
0
0
0
7
7
27
7
60
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
14
0
0
0
0
0
27
54
% K
% Leu:
0
0
0
0
0
14
0
0
0
47
7
7
0
0
7
% L
% Met:
0
0
7
0
0
0
7
0
0
7
0
7
7
0
0
% M
% Asn:
0
0
0
27
0
60
0
0
0
0
0
0
74
60
7
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
27
7
60
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
27
0
60
0
7
0
0
0
14
14
0
% R
% Ser:
0
0
0
0
0
20
0
60
0
0
0
0
0
0
14
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
7
27
27
67
67
0
0
0
0
7
14
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _