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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1L All Species: 32.42
Human Site: S317 Identified Species: 50.95
UniProt: O00429 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00429 NP_005681.2 736 81877 S317 V L A A Q Y Q S L L N S Y G E
Chimpanzee Pan troglodytes XP_520720 896 98575 S477 V L A A Q Y Q S L L N S Y G E
Rhesus Macaque Macaca mulatta XP_001086126 725 80517 S317 V L A A Q Y Q S L L N S Y G E
Dog Lupus familis XP_864886 736 81869 S317 V L A A Q Y Q S L L N S Y G E
Cat Felis silvestris
Mouse Mus musculus Q8K1M6 742 82640 S323 V L A A Q Y Q S L L N S Y G E
Rat Rattus norvegicus O35303 755 83890 S330 V L A A Q Y Q S L L N S Y G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073190 696 77727 R307 C L P E L K T R I N V L A A Q
Frog Xenopus laevis NP_001080183 698 77807 T317 V L A A Q Y Q T L L N S Y G E
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 D298 L L M H H I R D C L P E L K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 F309 L E K E V E E F K H F Q P G D
Honey Bee Apis mellifera XP_394947 721 81070 T317 V M V S Q F Q T L L N S Y G E
Nematode Worm Caenorhab. elegans P39055 830 93389 Y316 M E K D V A E Y K N Y Q P N D
Sea Urchin Strong. purpuratus XP_802061 717 80361 Q317 V M T S Q F Q Q L M A S F G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 E333 F A T A K E Y E S Y G D I T E
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 R352 Q T E Q E L A R Y G G V G A T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 98.5 99.1 N.A. 97.8 96.4 N.A. N.A. 89.8 87 86 N.A. 33.9 66.8 35.6 68.7
Protein Similarity: 100 79.9 98.5 99.5 N.A. 98.3 97.2 N.A. N.A. 91.8 90.9 90.3 N.A. 52.2 79.7 53.9 82.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 93.3 13.3 N.A. 6.6 66.6 0 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 100 26.6 N.A. 26.6 93.3 20 80
Percent
Protein Identity: N.A. N.A. N.A. 42.4 45.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 65.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 47 54 0 7 7 0 0 0 7 0 7 14 0 % A
% Cys: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 7 0 0 0 7 0 0 14 % D
% Glu: 0 14 7 14 7 14 14 7 0 0 0 7 0 0 67 % E
% Phe: 7 0 0 0 0 14 0 7 0 0 7 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 14 0 7 67 0 % G
% His: 0 0 0 7 7 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 0 0 7 0 0 % I
% Lys: 0 0 14 0 7 7 0 0 14 0 0 0 0 7 0 % K
% Leu: 14 60 0 0 7 7 0 0 60 60 0 7 7 0 0 % L
% Met: 7 14 7 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 14 54 0 0 7 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 7 0 14 0 0 % P
% Gln: 7 0 0 7 60 0 60 7 0 0 0 14 0 0 7 % Q
% Arg: 0 0 0 0 0 0 7 14 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 14 0 0 0 40 7 0 0 60 0 0 0 % S
% Thr: 0 7 14 0 0 0 7 14 0 0 0 0 0 7 14 % T
% Val: 60 0 7 0 14 0 0 0 0 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 47 7 7 7 7 7 0 54 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _