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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1L All Species: 36.97
Human Site: S330 Identified Species: 58.1
UniProt: O00429 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00429 NP_005681.2 736 81877 S330 G E P V D D K S A T L L Q L I
Chimpanzee Pan troglodytes XP_520720 896 98575 S490 G E P V D D K S A T L L Q L I
Rhesus Macaque Macaca mulatta XP_001086126 725 80517 S330 G E P V D D K S A T L L Q L I
Dog Lupus familis XP_864886 736 81869 S330 G E P V D D K S A T L L Q L I
Cat Felis silvestris
Mouse Mus musculus Q8K1M6 742 82640 S336 G E P V D D K S A T L L Q L I
Rat Rattus norvegicus O35303 755 83890 S343 G E P V D D K S A T L L Q L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073190 696 77727 N320 A Q Y Q S L L N S Y G E P V E
Frog Xenopus laevis NP_001080183 698 77807 S330 G E P V E D K S A T L L Q L I
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 S311 K T R I N V L S A Q Y Q S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 K322 G D A S I K T K A M L Q M I Q
Honey Bee Apis mellifera XP_394947 721 81070 S330 G E D V S D K S Q T L L Q I I
Nematode Worm Caenorhab. elegans P39055 830 93389 K329 N D P G R K T K A L L Q M V T
Sea Urchin Strong. purpuratus XP_802061 717 80361 S330 G E P V E D K S Q T L L Q I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 G346 T E S R G G Q G A L L L S F I
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 A365 A T T N E S R A S L V L Q L M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 98.5 99.1 N.A. 97.8 96.4 N.A. N.A. 89.8 87 86 N.A. 33.9 66.8 35.6 68.7
Protein Similarity: 100 79.9 98.5 99.5 N.A. 98.3 97.2 N.A. N.A. 91.8 90.9 90.3 N.A. 52.2 79.7 53.9 82.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 93.3 20 N.A. 20 73.3 20 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 26.6 100 40 N.A. 33.3 80 33.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 42.4 45.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 65.2 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 0 0 0 0 7 74 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 7 0 40 60 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 67 0 0 20 0 0 0 0 0 0 7 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 67 0 0 7 7 7 0 7 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 0 0 0 0 0 0 0 0 20 67 % I
% Lys: 7 0 0 0 0 14 60 14 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 7 14 0 0 20 80 74 0 60 7 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 14 0 7 % M
% Asn: 7 0 0 7 7 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 7 0 7 0 0 7 0 14 7 0 20 67 0 7 % Q
% Arg: 0 0 7 7 7 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 7 14 7 0 67 14 0 0 0 14 0 0 % S
% Thr: 7 14 7 0 0 0 14 0 0 60 0 0 0 0 7 % T
% Val: 0 0 0 60 0 7 0 0 0 0 7 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _