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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
21.82
Human Site:
S538
Identified Species:
34.29
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
S538
D
K
S
S
K
V
P
S
A
L
A
P
A
S
Q
Chimpanzee
Pan troglodytes
XP_520720
896
98575
S698
D
K
S
S
K
V
P
S
A
L
A
P
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
A527
L
A
R
E
L
P
S
A
V
S
R
D
K
S
S
Dog
Lupus familis
XP_864886
736
81869
S538
D
K
S
Y
K
V
P
S
A
L
A
P
A
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
S544
D
K
S
S
K
V
P
S
A
L
A
P
A
S
Q
Rat
Rattus norvegicus
O35303
755
83890
S551
D
K
S
S
K
V
P
S
A
L
A
P
A
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
C505
H
P
D
F
A
D
A
C
G
L
M
N
N
N
I
Frog
Xenopus laevis
NP_001080183
698
77807
Q515
I
N
N
N
I
E
E
Q
R
R
N
R
I
S
R
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
P498
A
Y
I
N
T
K
H
P
D
F
A
D
A
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
F537
G
G
S
R
P
Y
W
F
V
L
T
S
E
S
I
Honey Bee
Apis mellifera
XP_394947
721
81070
N523
N
V
D
H
I
K
H
N
R
K
V
P
S
T
T
Nematode Worm
Caenorhab. elegans
P39055
830
93389
W541
V
R
G
S
K
D
N
W
F
V
L
M
S
D
S
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
T520
R
E
N
S
R
K
S
T
R
L
A
E
S
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
T549
D
T
V
E
P
E
R
T
A
S
S
G
S
Q
I
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
N564
S
K
L
S
Q
Q
E
N
G
Q
T
N
G
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
6.6
93.3
N.A.
100
100
N.A.
N.A.
6.6
6.6
13.3
N.A.
20
6.6
13.3
20
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
N.A.
13.3
26.6
20
N.A.
20
33.3
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
7
7
40
0
47
0
40
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
40
0
14
0
0
14
0
0
7
0
0
14
0
7
0
% D
% Glu:
0
7
0
14
0
14
14
0
0
0
0
7
7
0
0
% E
% Phe:
0
0
0
7
0
0
0
7
7
7
0
0
0
0
0
% F
% Gly:
7
7
7
0
0
0
0
0
14
0
0
7
7
0
7
% G
% His:
7
0
0
7
0
0
14
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
14
0
0
0
0
0
0
0
7
7
20
% I
% Lys:
0
40
0
0
40
20
0
0
0
7
0
0
7
0
0
% K
% Leu:
7
0
7
0
7
0
0
0
0
54
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
7
7
14
14
0
0
7
14
0
0
7
14
7
7
7
% N
% Pro:
0
7
0
0
14
7
34
7
0
0
0
40
0
0
7
% P
% Gln:
0
0
0
0
7
7
0
7
0
7
0
0
0
7
34
% Q
% Arg:
7
7
7
7
7
0
7
0
20
7
7
7
0
0
7
% R
% Ser:
7
0
40
47
0
0
14
34
0
14
7
7
27
54
14
% S
% Thr:
0
7
0
0
7
0
0
14
0
0
14
0
0
7
7
% T
% Val:
7
7
7
0
0
34
0
0
14
7
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _