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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
21.21
Human Site:
S616
Identified Species:
33.33
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
S616
P
I
P
I
M
P
A
S
P
Q
K
G
H
A
V
Chimpanzee
Pan troglodytes
XP_520720
896
98575
S776
P
I
P
I
M
P
A
S
P
Q
K
G
H
A
V
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
S605
P
I
P
I
M
P
A
S
P
Q
K
G
H
A
V
Dog
Lupus familis
XP_864886
736
81869
S616
P
I
P
I
M
P
A
S
P
Q
K
G
H
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
S622
P
I
P
I
M
P
A
S
P
Q
K
G
H
A
V
Rat
Rattus norvegicus
O35303
755
83890
I629
A
E
E
K
S
K
P
I
P
I
M
P
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
V583
S
P
Q
K
G
H
A
V
N
L
L
D
V
P
V
Frog
Xenopus laevis
NP_001080183
698
77807
P593
N
L
L
D
V
P
V
P
V
A
R
K
L
S
A
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
H576
P
A
S
P
Q
K
G
H
A
V
N
L
L
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
S615
D
V
E
S
W
K
A
S
F
L
R
A
G
V
Y
Honey Bee
Apis mellifera
XP_394947
721
81070
S601
I
I
E
V
Q
K
A
S
S
Q
Q
K
P
V
N
Nematode Worm
Caenorhab. elegans
P39055
830
93389
F619
I
D
A
W
K
A
S
F
L
R
A
G
V
Y
P
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
K598
S
S
P
K
V
E
R
K
R
P
G
I
N
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
N627
T
T
Q
E
V
Y
Q
N
L
S
T
I
Y
L
K
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
L642
N
I
E
D
F
R
N
L
Q
I
S
D
F
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
13.3
26.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
13.3
33.3
13.3
N.A.
26.6
40
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
7
54
0
7
7
7
7
7
34
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
14
0
0
0
0
0
0
0
14
0
7
0
% D
% Glu:
0
7
27
7
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
7
7
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
7
0
0
0
7
40
7
0
0
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
34
0
0
% H
% Ile:
14
47
0
34
0
0
0
7
0
14
0
14
0
0
0
% I
% Lys:
0
0
0
20
7
27
0
7
0
0
34
14
0
0
7
% K
% Leu:
0
7
7
0
0
0
0
7
14
14
7
7
14
14
14
% L
% Met:
0
0
0
0
34
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
7
7
7
0
7
0
7
0
7
% N
% Pro:
40
7
40
7
0
40
7
7
40
7
0
7
7
7
14
% P
% Gln:
0
0
14
0
14
0
7
0
7
40
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
7
0
7
7
14
0
0
0
0
% R
% Ser:
14
7
7
7
7
0
7
47
7
7
7
0
0
20
0
% S
% Thr:
7
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% T
% Val:
0
7
0
7
20
0
7
7
7
7
0
0
14
14
47
% V
% Trp:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _