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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
19.39
Human Site:
T586
Identified Species:
30.48
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
T586
D
G
V
Q
E
P
T
T
G
N
W
R
G
M
L
Chimpanzee
Pan troglodytes
XP_520720
896
98575
T746
D
G
V
Q
E
P
T
T
G
N
W
R
G
M
L
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
T575
D
G
V
Q
E
P
T
T
G
N
W
R
G
M
L
Dog
Lupus familis
XP_864886
736
81869
T586
D
G
G
Q
E
P
T
T
G
N
W
R
G
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
T592
D
G
G
Q
E
P
T
T
G
N
W
R
G
M
L
Rat
Rattus norvegicus
O35303
755
83890
G599
D
G
G
R
I
G
D
G
G
Q
E
P
T
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
L553
T
G
N
W
R
G
M
L
K
S
S
K
A
E
E
Frog
Xenopus laevis
NP_001080183
698
77807
A563
M
K
A
K
G
E
E
A
S
V
E
E
K
N
K
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
W546
Q
E
G
G
T
G
T
W
R
G
M
L
K
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
F585
R
R
V
T
F
A
L
F
S
P
D
G
R
N
V
Honey Bee
Apis mellifera
XP_394947
721
81070
I571
R
T
D
S
T
S
S
I
D
N
S
P
V
R
N
Nematode Worm
Caenorhab. elegans
P39055
830
93389
Y589
N
H
K
F
A
L
F
Y
P
D
G
K
N
I
Y
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
G568
W
V
P
S
W
V
R
G
S
A
P
N
L
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
S597
T
S
W
S
G
F
S
S
I
F
R
G
S
D
G
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
G612
K
F
L
N
Y
F
F
G
K
D
K
K
G
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
6.6
0
6.6
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
N.A.
20
6.6
6.6
N.A.
13.3
13.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
0
7
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
0
7
0
0
0
7
0
7
14
7
0
0
7
0
% D
% Glu:
0
7
0
0
34
7
7
0
0
0
14
7
0
7
7
% E
% Phe:
0
7
0
7
7
14
14
7
0
7
0
0
0
0
0
% F
% Gly:
0
47
27
7
14
20
0
20
40
7
7
14
40
0
20
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
7
7
0
0
0
0
7
0
% I
% Lys:
7
7
7
7
0
0
0
0
14
0
7
20
14
14
7
% K
% Leu:
0
0
7
0
0
7
7
7
0
0
0
7
7
0
34
% L
% Met:
7
0
0
0
0
0
7
0
0
0
7
0
0
34
0
% M
% Asn:
7
0
7
7
0
0
0
0
0
40
0
7
7
14
7
% N
% Pro:
0
0
7
0
0
34
0
0
7
7
7
14
0
0
7
% P
% Gln:
7
0
0
34
0
0
0
0
0
7
0
0
0
7
0
% Q
% Arg:
14
7
0
7
7
0
7
0
7
0
7
34
7
7
0
% R
% Ser:
0
7
0
20
0
7
14
7
20
7
14
0
7
0
7
% S
% Thr:
14
7
0
7
14
0
40
34
0
0
0
0
7
7
0
% T
% Val:
0
7
27
0
0
7
0
0
0
7
0
0
7
0
7
% V
% Trp:
7
0
7
7
7
0
0
7
0
0
34
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _