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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1L All Species: 46.06
Human Site: T59 Identified Species: 72.38
UniProt: O00429 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00429 NP_005681.2 736 81877 T59 P R G T G I V T R R P L I L Q
Chimpanzee Pan troglodytes XP_520720 896 98575 T112 V G A A A V P T P A P A F G A
Rhesus Macaque Macaca mulatta XP_001086126 725 80517 T59 P R G T G I V T R R P L I L Q
Dog Lupus familis XP_864886 736 81869 T59 P R G T G I V T R R P L I L Q
Cat Felis silvestris
Mouse Mus musculus Q8K1M6 742 82640 T59 P R G T G V V T R R P L I L Q
Rat Rattus norvegicus O35303 755 83890 T59 P R G T G V V T R R P L I L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073190 696 77727 T59 P R G T G V V T R R P L I L Q
Frog Xenopus laevis NP_001080183 698 77807 T59 P R G T G V V T R R P L I L Q
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 T59 P R G T G I V T R R P L I L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 P53 F V G K D F L P R G S G I V T
Honey Bee Apis mellifera XP_394947 721 81070 T59 P R G T G I V T R R P L I L Q
Nematode Worm Caenorhab. elegans P39055 830 93389 E51 A G K S S V L E N F V G K D F
Sea Urchin Strong. purpuratus XP_802061 717 80361 T59 P R G N G I V T R R P L V L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 G72 G R D F L P R G N D I C T R R
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 T62 P R G T G I V T R R P L V L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 98.5 99.1 N.A. 97.8 96.4 N.A. N.A. 89.8 87 86 N.A. 33.9 66.8 35.6 68.7
Protein Similarity: 100 79.9 98.5 99.5 N.A. 98.3 97.2 N.A. N.A. 91.8 90.9 90.3 N.A. 52.2 79.7 53.9 82.2
P-Site Identity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 93.3 100 N.A. 20 100 0 86.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 33.3 100 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. 42.4 45.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 65.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 93.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 7 0 0 0 0 7 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 0 7 0 0 0 0 7 0 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 7 0 7 0 0 0 7 0 0 7 0 7 % F
% Gly: 7 14 80 0 74 0 0 7 0 7 0 14 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 47 0 0 0 0 7 0 67 0 0 % I
% Lys: 0 0 7 7 0 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 0 0 0 0 7 0 14 0 0 0 0 74 0 74 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 14 0 0 0 0 0 0 % N
% Pro: 74 0 0 0 0 7 7 7 7 0 80 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74 % Q
% Arg: 0 80 0 0 0 0 7 0 80 74 0 0 0 7 7 % R
% Ser: 0 0 0 7 7 0 0 0 0 0 7 0 0 0 0 % S
% Thr: 0 0 0 67 0 0 0 80 0 0 0 0 7 0 7 % T
% Val: 7 7 0 0 0 40 74 0 0 0 7 0 14 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _