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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
27.58
Human Site:
T78
Identified Species:
43.33
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
T78
S
Q
E
D
K
R
K
T
T
G
E
E
N
G
V
Chimpanzee
Pan troglodytes
XP_520720
896
98575
L131
A
L
R
G
A
P
G
L
S
G
L
C
R
T
R
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
T78
S
Q
E
D
K
R
K
T
T
G
E
E
N
G
V
Dog
Lupus familis
XP_864886
736
81869
T78
S
P
E
D
K
R
K
T
T
G
E
E
N
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
T78
S
P
E
D
K
R
K
T
T
G
E
E
N
G
K
Rat
Rattus norvegicus
O35303
755
83890
T78
S
P
E
D
K
R
K
T
T
G
E
E
N
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
T78
S
P
E
D
G
R
K
T
A
G
D
E
N
E
I
Frog
Xenopus laevis
NP_001080183
698
77807
T78
S
S
D
D
R
R
K
T
S
G
D
E
N
G
V
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
T78
D
P
E
D
R
R
K
T
S
E
E
N
G
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
V72
I
L
Q
L
I
N
G
V
T
E
Y
G
E
F
L
Honey Bee
Apis mellifera
XP_394947
721
81070
R78
P
K
D
D
R
E
H
R
S
A
E
N
G
T
L
Nematode Worm
Caenorhab. elegans
P39055
830
93389
P70
S
G
I
V
T
R
R
P
L
I
L
Q
L
I
Q
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
A78
D
P
E
D
K
R
G
A
S
G
E
G
E
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
S91
Q
L
V
Q
T
K
P
S
S
D
G
G
S
D
E
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
E81
S
P
N
S
P
L
I
E
E
D
D
N
S
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
80
N.A.
N.A.
60
66.6
40
N.A.
6.6
13.3
13.3
46.6
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
80
N.A.
N.A.
73.3
93.3
53.3
N.A.
20
46.6
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
7
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
14
0
14
67
0
0
0
0
0
14
20
0
0
14
7
% D
% Glu:
0
0
54
0
0
7
0
7
7
14
54
47
14
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
7
7
0
20
0
0
60
7
20
14
40
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
7
0
7
0
0
7
0
0
0
7
7
% I
% Lys:
0
7
0
0
40
7
54
0
0
0
0
0
0
0
7
% K
% Leu:
0
20
0
7
0
7
0
7
7
0
14
0
7
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
20
47
0
7
% N
% Pro:
7
47
0
0
7
7
7
7
0
0
0
0
0
0
7
% P
% Gln:
7
14
7
7
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
7
0
20
67
7
7
0
0
0
0
7
0
7
% R
% Ser:
60
7
0
7
0
0
0
7
40
0
0
0
14
0
0
% S
% Thr:
0
0
0
0
14
0
0
54
40
0
0
0
0
14
0
% T
% Val:
0
0
7
7
0
0
0
7
0
0
0
0
0
14
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _