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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT5
All Species:
12.12
Human Site:
S20
Identified Species:
24.24
UniProt:
O00445
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00445
NP_003171.2
386
42900
S20
P
D
T
P
P
D
S
S
R
I
S
H
G
P
V
Chimpanzee
Pan troglodytes
XP_001162436
418
47136
N49
K
L
K
E
K
F
M
N
E
L
H
K
I
P
L
Rhesus Macaque
Macaca mulatta
XP_001087504
1219
134080
T853
K
M
A
G
G
K
R
T
P
A
F
Q
L
P
L
Dog
Lupus familis
XP_533585
386
42961
S20
P
D
T
P
P
D
S
S
R
I
R
H
G
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0N5
386
43111
S20
P
K
T
P
P
D
S
S
R
I
R
Q
G
A
V
Rat
Rattus norvegicus
P47861
386
43108
S20
P
E
T
P
P
D
S
S
R
I
R
Q
G
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506668
439
49264
N66
K
L
K
E
K
F
M
N
G
L
N
K
I
P
L
Chicken
Gallus gallus
P47191
424
47487
N51
N
L
K
K
K
F
M
N
E
L
N
K
I
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696277
430
48125
N59
D
I
K
N
K
F
L
N
E
M
D
K
L
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
V103
V
G
E
V
V
T
E
V
I
A
E
R
T
G
L
Honey Bee
Apis mellifera
NP_001139207
434
48848
E63
Q
M
E
N
L
G
K
E
I
A
E
E
M
G
I
Nematode Worm
Caenorhab. elegans
P34693
441
49885
K65
V
K
D
V
V
K
E
K
V
M
Q
Q
T
G
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.6
31.3
94.5
N.A.
91.1
91.1
N.A.
54.4
56.1
N.A.
52.3
N.A.
44.5
48.6
46.7
N.A.
Protein Similarity:
100
75.5
31.4
96.3
N.A.
94.5
94.8
N.A.
71.5
73.5
N.A.
71.6
N.A.
61.5
65.9
62.8
N.A.
P-Site Identity:
100
6.6
6.6
93.3
N.A.
73.3
73.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
0
0
N.A.
P-Site Similarity:
100
26.6
20
93.3
N.A.
73.3
80
N.A.
33.3
33.3
N.A.
26.6
N.A.
6.6
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
25
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
9
0
0
34
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
17
17
0
0
17
9
25
0
17
9
0
0
0
% E
% Phe:
0
0
0
0
0
34
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
9
9
9
0
0
9
0
0
0
34
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
17
34
0
0
25
0
9
% I
% Lys:
25
17
34
9
34
17
9
9
0
0
0
34
0
0
0
% K
% Leu:
0
25
0
0
9
0
9
0
0
25
0
0
17
0
50
% L
% Met:
0
17
0
0
0
0
25
0
0
17
0
0
9
0
9
% M
% Asn:
9
0
0
17
0
0
0
34
0
0
17
0
0
0
0
% N
% Pro:
34
0
0
34
34
0
0
0
9
0
0
0
0
59
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
9
34
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
34
0
25
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
34
34
0
0
9
0
0
0
0
% S
% Thr:
0
0
34
0
0
9
0
9
0
0
0
0
17
0
0
% T
% Val:
17
0
0
17
17
0
0
9
9
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _