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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT5 All Species: 17.27
Human Site: S63 Identified Species: 34.55
UniProt: O00445 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00445 NP_003171.2 386 42900 S63 R R R T G K K S Q A Q A Q V H
Chimpanzee Pan troglodytes XP_001162436 418 47136 K92 F K K K N K K K G K E K G G K
Rhesus Macaque Macaca mulatta XP_001087504 1219 134080 S896 R R R T G K K S Q A Q A Q V H
Dog Lupus familis XP_533585 386 42961 S63 R R R L G K K S Q A Q A Q V H
Cat Felis silvestris
Mouse Mus musculus Q9R0N5 386 43111 S63 R R R M G K K S Q A Q A Q V H
Rat Rattus norvegicus P47861 386 43108 S63 R R R M G K K S Q A Q A Q V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506668 439 49264 K109 F K K K N K K K G K E K G G K
Chicken Gallus gallus P47191 424 47487 K94 F K K K N K K K G K E K G G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696277 430 48125 K102 L K K K K G K K G K K G K G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 G146 K K R R T K D G K G K K G V D
Honey Bee Apis mellifera NP_001139207 434 48848 G106 R K R R S K D G K K G L K G A
Nematode Worm Caenorhab. elegans P34693 441 49885 K108 G K K R H G E K N K K G G L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.6 31.3 94.5 N.A. 91.1 91.1 N.A. 54.4 56.1 N.A. 52.3 N.A. 44.5 48.6 46.7 N.A.
Protein Similarity: 100 75.5 31.4 96.3 N.A. 94.5 94.8 N.A. 71.5 73.5 N.A. 71.6 N.A. 61.5 65.9 62.8 N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. 13.3 13.3 N.A. 6.6 N.A. 20 20 0 N.A.
P-Site Similarity: 100 33.3 100 93.3 N.A. 93.3 93.3 N.A. 33.3 33.3 N.A. 33.3 N.A. 46.6 40 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 42 0 42 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 17 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 25 0 0 0 0 % E
% Phe: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 42 17 0 17 34 9 9 17 42 42 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 42 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 42 34 9 84 75 42 17 50 25 34 17 0 34 % K
% Leu: 9 0 0 9 0 0 0 0 0 0 0 9 0 9 0 % L
% Met: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 25 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 42 0 42 0 42 0 0 % Q
% Arg: 50 42 59 25 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 42 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _