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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFRA2
All Species:
8.18
Human Site:
S441
Identified Species:
22.5
UniProt:
O00451
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00451
NP_001486.4
464
51544
S441
N
K
V
I
K
P
N
S
G
P
S
R
A
R
P
Chimpanzee
Pan troglodytes
XP_001146351
321
35166
S298
N
K
V
I
K
P
N
S
G
P
S
R
A
R
P
Rhesus Macaque
Macaca mulatta
XP_001105178
417
45200
G395
K
V
I
K
P
N
S
G
P
S
R
A
R
P
S
Dog
Lupus familis
XP_851478
393
43687
G371
K
V
I
K
P
N
S
G
P
C
R
A
R
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O08842
463
51580
S441
K
K
V
I
K
L
Y
S
G
S
C
R
A
R
L
Rat
Rattus norvegicus
Q62997
468
51631
T434
G
A
S
S
H
I
T
T
K
S
M
A
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513939
304
33762
K282
G
G
K
L
Q
V
A
K
D
F
R
N
A
P
G
Chicken
Gallus gallus
O13157
465
51891
D439
P
D
Q
K
T
F
V
D
Q
K
A
A
G
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693326
418
46552
I396
R
T
N
L
Q
P
A
I
I
T
K
H
V
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.9
73.7
81.6
N.A.
93.7
48
N.A.
34.2
75.4
N.A.
55.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.9
76.2
82.9
N.A.
96.1
65.3
N.A.
44.8
86.4
N.A.
67
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
60
13.3
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
60
20
N.A.
20
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
23
0
0
0
12
45
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
12
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% F
% Gly:
23
12
0
0
0
0
0
23
34
0
0
0
12
0
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
23
34
0
12
0
12
12
0
0
0
0
12
0
% I
% Lys:
34
34
12
34
34
0
0
12
12
12
12
0
0
0
0
% K
% Leu:
0
0
0
23
0
12
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
23
0
12
0
0
23
23
0
0
0
0
12
0
0
12
% N
% Pro:
12
0
0
0
23
34
0
0
23
23
0
0
0
45
34
% P
% Gln:
0
0
12
0
23
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
34
34
23
34
12
% R
% Ser:
0
0
12
12
0
0
23
34
0
34
23
0
0
12
23
% S
% Thr:
0
12
0
0
12
0
12
12
0
12
0
0
0
0
0
% T
% Val:
0
23
34
0
0
12
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _