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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
12.12
Human Site:
S227
Identified Species:
20.51
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S227
F
S
P
I
Y
D
K
S
A
Q
E
W
N
L
E
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S227
F
S
P
I
Y
D
K
S
A
Q
E
W
N
L
E
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S422
F
S
P
I
Y
D
K
S
A
Q
A
W
N
L
E
Dog
Lupus familis
XP_545005
885
101736
H233
F
S
P
I
Y
D
N
H
T
Q
V
W
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
A227
F
L
P
V
Y
D
N
A
S
Q
A
W
N
I
E
Rat
Rattus norvegicus
Q4FZV0
881
101203
T227
F
L
P
L
Y
D
N
T
S
Q
A
W
T
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
V184
E
I
E
S
I
F
N
V
V
G
S
K
P
I
A
Frog
Xenopus laevis
NP_001087135
874
101196
K223
F
V
P
V
F
D
D
K
T
S
Q
W
T
V
L
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
A248
T
S
P
K
Y
D
P
A
D
S
S
W
S
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
G238
V
D
V
S
R
V
N
G
S
Y
W
N
M
H
I
Honey Bee
Apis mellifera
XP_392850
1110
128827
C306
E
I
L
E
C
G
V
C
S
K
Y
K
T
T
N
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
G233
W
K
T
R
F
A
H
G
K
W
K
V
A
F
E
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
F86
R
D
N
W
T
Y
T
F
N
F
A
V
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
A227
F
F
D
D
Y
K
R
A
Y
L
H
V
T
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
93.3
66.6
N.A.
53.3
46.6
N.A.
N.A.
0
26.6
40
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
80
73.3
N.A.
N.A.
6.6
53.3
60
N.A.
6.6
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
22
22
0
29
0
8
8
8
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
8
0
58
8
0
8
0
0
0
0
0
8
% D
% Glu:
15
0
8
8
0
0
0
0
0
0
15
0
0
0
65
% E
% Phe:
58
8
0
0
15
8
0
8
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
15
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
8
0
0
8
0
% H
% Ile:
0
15
0
29
8
0
0
0
0
0
0
0
0
22
8
% I
% Lys:
0
8
0
8
0
8
22
8
8
8
8
15
0
0
0
% K
% Leu:
0
15
8
8
0
0
0
0
0
8
0
0
0
29
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
36
0
8
0
0
8
29
0
8
% N
% Pro:
0
0
58
0
0
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
43
8
0
0
0
0
% Q
% Arg:
8
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
36
0
15
0
0
0
22
29
15
15
0
15
8
0
% S
% Thr:
8
0
8
0
8
0
8
8
15
0
0
0
36
8
0
% T
% Val:
8
8
8
15
0
8
8
8
8
0
8
22
0
15
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
8
8
58
0
0
0
% W
% Tyr:
0
0
0
0
58
8
0
0
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _