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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MANBA All Species: 18.48
Human Site: S24 Identified Species: 31.28
UniProt: O00462 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00462 NP_005899.3 879 100895 S24 T A A E L S Y S L R G N W S I
Chimpanzee Pan troglodytes XP_517370 879 100802 S24 T A A E L S Y S L R G N W S I
Rhesus Macaque Macaca mulatta XP_001101549 1074 122458 V219 E A D S V G T V F N L E K T V
Dog Lupus familis XP_545005 885 101736 S30 P A L S R S L S L R G G W R I
Cat Felis silvestris
Mouse Mus musculus Q8K2I4 879 100812 S24 V V A G P S Y S L S G S W R V
Rat Rattus norvegicus Q4FZV0 881 101203 S24 M A A G P S Y S L R G S W R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420666 822 94668
Frog Xenopus laevis NP_001087135 874 101196 S21 H D R S Q T F S L N G R W E I
Zebra Danio Brachydanio rerio XP_002664183 901 102422 S38 S L G D N M V S L N G K W Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649436 908 103501 K33 V C S G Q C D K V E V I E L S
Honey Bee Apis mellifera XP_392850 1110 128827 S113 S H K S N H T S P I H E K T V
Nematode Worm Caenorhab. elegans Q93324 900 103960 N27 H G Y N T L V N L A G N W E F
Sea Urchin Strong. purpuratus XP_001186463 724 81612
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q75W54 944 107642 Q27 E V D V N G V Q L T T T N P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 76.5 80.4 N.A. 75.7 75.2 N.A. N.A. 64.2 58.1 53.8 N.A. 34.6 29.9 33.3 39.2
Protein Similarity: 100 99.5 79.2 87.6 N.A. 85.8 86.6 N.A. N.A. 77.5 74.2 70.4 N.A. 52.2 47.2 54.1 52.3
P-Site Identity: 100 100 6.6 53.3 N.A. 46.6 60 N.A. N.A. 0 33.3 26.6 N.A. 0 6.6 26.6 0
P-Site Similarity: 100 100 26.6 53.3 N.A. 60 73.3 N.A. N.A. 0 46.6 46.6 N.A. 13.3 26.6 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 36 29 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 8 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 0 15 0 0 0 0 0 8 0 15 8 15 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 8 % F
% Gly: 0 8 8 22 0 15 0 0 0 0 58 8 0 0 0 % G
% His: 15 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 29 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 0 8 15 0 0 % K
% Leu: 0 8 8 0 15 8 8 0 65 0 8 0 0 8 8 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 22 0 0 8 0 22 0 22 8 0 0 % N
% Pro: 8 0 0 0 15 0 0 0 8 0 0 0 0 8 8 % P
% Gln: 0 0 0 0 15 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 29 0 8 0 22 0 % R
% Ser: 15 0 8 29 0 36 0 58 0 8 0 15 0 15 8 % S
% Thr: 15 0 0 0 8 8 15 0 0 8 8 8 0 15 0 % T
% Val: 15 15 0 8 8 0 22 8 8 0 8 0 0 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 % W
% Tyr: 0 0 8 0 0 0 29 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _