KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
26.06
Human Site:
S243
Identified Species:
44.1
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S243
E
S
T
F
D
V
V
S
S
K
P
V
G
G
Q
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S243
E
S
T
F
D
V
V
S
S
K
P
V
G
G
Q
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S438
E
A
T
F
D
V
V
S
S
K
P
V
G
G
Q
Dog
Lupus familis
XP_545005
885
101736
S249
E
S
S
F
D
V
V
S
P
K
P
I
S
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
S243
K
A
S
F
D
V
A
S
S
K
S
V
G
G
Q
Rat
Rattus norvegicus
Q4FZV0
881
101203
S243
E
A
S
F
D
V
V
S
T
K
P
V
G
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
K200
L
A
T
V
N
I
P
K
L
Q
T
Q
Q
T
Y
Frog
Xenopus laevis
NP_001087135
874
101196
T239
E
S
V
L
D
V
I
T
N
G
P
L
P
G
N
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
V264
E
L
F
F
D
V
V
V
A
S
K
G
L
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
W254
C
F
L
D
A
G
G
W
Q
N
F
N
G
R
L
Honey Bee
Apis mellifera
XP_392850
1110
128827
N322
I
H
Y
E
E
H
V
N
T
C
L
Q
K
Q
H
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
R249
D
T
F
H
Y
G
A
R
T
I
E
Y
S
V
Q
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
L102
T
N
K
H
N
V
K
L
V
S
K
G
L
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
T243
E
N
K
S
T
W
N
T
E
C
S
V
N
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
80
N.A.
N.A.
6.6
40
33.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
100
N.A.
N.A.
33.3
66.6
40
N.A.
6.6
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
0
8
0
15
0
8
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
8
0
0
8
58
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
58
0
0
8
8
0
0
0
8
0
8
0
0
0
0
% E
% Phe:
0
8
15
50
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
8
0
0
8
0
15
43
50
0
% G
% His:
0
8
0
15
0
8
0
0
0
0
0
0
0
0
15
% H
% Ile:
8
0
0
0
0
8
8
0
0
8
0
8
0
8
0
% I
% Lys:
8
0
15
0
0
0
8
8
0
43
15
0
8
0
0
% K
% Leu:
8
8
8
8
0
0
0
8
8
0
8
8
15
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
15
0
8
8
8
8
0
8
8
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
43
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
15
8
8
58
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% R
% Ser:
0
29
22
8
0
0
0
43
29
15
15
0
15
0
0
% S
% Thr:
8
8
29
0
8
0
0
15
22
0
8
0
0
8
8
% T
% Val:
0
0
8
8
0
65
50
8
8
0
0
43
0
15
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _