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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
29.39
Human Site:
S506
Identified Species:
49.74
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S506
S
R
P
F
I
T
S
S
P
T
N
G
A
E
T
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S506
S
R
P
F
I
T
S
S
P
T
N
G
A
E
T
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S701
S
R
P
F
I
T
S
S
P
T
N
G
A
E
T
Dog
Lupus familis
XP_545005
885
101736
S512
S
R
P
F
I
I
S
S
P
T
N
G
A
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
S506
S
R
P
F
I
A
S
S
P
T
N
G
M
K
T
Rat
Rattus norvegicus
Q4FZV0
881
101203
S506
S
R
P
F
I
A
S
S
P
T
N
G
V
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
L454
V
S
S
P
T
N
G
L
E
S
I
K
E
G
W
Frog
Xenopus laevis
NP_001087135
874
101196
S502
T
R
P
F
I
S
S
S
P
T
N
G
K
E
S
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
S525
S
R
P
F
L
V
S
S
P
T
N
G
V
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
R523
K
L
V
S
H
S
S
R
P
Q
P
L
V
S
S
Honey Bee
Apis mellifera
XP_392850
1110
128827
A706
A
G
N
N
E
N
E
A
A
L
Y
D
N
W
Y
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
P512
I
P
F
I
M
S
S
P
S
N
G
V
E
T
E
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
F356
K
I
N
T
I
P
I
F
I
K
G
S
N
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
F516
Q
G
S
M
W
D
G
F
A
D
G
K
G
N
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
0
73.3
73.3
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
93.3
86.6
N.A.
26.6
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
15
0
8
15
0
0
0
29
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
8
0
8
0
0
0
15
43
8
% E
% Phe:
0
0
8
58
0
0
0
15
0
0
0
0
0
0
8
% F
% Gly:
0
15
0
0
0
0
15
0
0
0
22
58
8
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
58
8
8
0
8
0
8
0
0
0
8
% I
% Lys:
15
0
0
0
0
0
0
0
0
8
0
15
8
15
0
% K
% Leu:
0
8
0
0
8
0
0
8
0
8
0
8
0
0
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
8
0
15
0
0
0
8
58
0
15
8
0
% N
% Pro:
0
8
58
8
0
8
0
8
65
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
58
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
50
8
15
8
0
22
72
58
8
8
0
8
0
8
29
% S
% Thr:
8
0
0
8
8
22
0
0
0
58
0
0
0
8
36
% T
% Val:
8
0
8
0
0
8
0
0
0
0
0
8
22
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _