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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
17.88
Human Site:
S608
Identified Species:
30.26
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S608
L
H
F
K
L
P
Q
S
T
D
P
L
R
T
F
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S608
L
H
F
K
L
P
Q
S
T
D
P
L
R
T
F
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S803
L
H
F
K
L
P
E
S
T
D
P
L
R
T
F
Dog
Lupus familis
XP_545005
885
101736
S614
F
H
F
K
L
P
E
S
T
D
P
L
Q
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
G608
M
H
F
K
L
P
Q
G
T
D
P
L
R
T
F
Rat
Rattus norvegicus
Q4FZV0
881
101203
R608
L
H
F
Q
L
P
Q
R
R
D
P
V
R
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
K556
P
Q
T
T
D
P
I
K
K
F
K
D
M
I
Y
Frog
Xenopus laevis
NP_001087135
874
101196
N604
L
H
Y
K
N
P
E
N
N
D
P
I
K
E
F
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
S627
L
H
Y
I
L
P
N
S
T
D
S
V
Q
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
L625
I
A
L
V
E
R
H
L
P
L
P
F
P
E
N
Honey Bee
Apis mellifera
XP_392850
1110
128827
Y808
F
Q
S
L
P
S
I
Y
T
M
L
P
V
A
K
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
C614
H
L
P
I
P
A
E
C
G
S
K
S
V
S
D
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
S458
H
P
S
V
I
A
W
S
A
N
N
E
N
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
L618
M
Y
G
T
P
E
N
L
D
D
F
C
L
K
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
93.3
80
N.A.
86.6
66.6
N.A.
N.A.
6.6
46.6
46.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
80
N.A.
N.A.
13.3
80
73.3
N.A.
13.3
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
15
0
0
8
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
65
0
8
0
0
8
% D
% Glu:
0
0
0
0
8
8
29
0
0
0
0
8
0
22
0
% E
% Phe:
15
0
43
0
0
0
0
0
0
8
8
8
0
0
50
% F
% Gly:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
8
% G
% His:
15
58
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
15
8
0
15
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
0
43
0
0
0
8
8
0
15
0
8
8
8
% K
% Leu:
43
8
8
8
50
0
0
15
0
8
8
36
8
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
15
8
8
8
8
0
8
0
8
% N
% Pro:
8
8
8
0
22
65
0
0
8
0
58
8
8
0
0
% P
% Gln:
0
15
0
8
0
0
29
0
0
0
0
0
15
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
8
0
0
0
36
8
0
% R
% Ser:
0
0
15
0
0
8
0
43
0
8
8
8
0
8
0
% S
% Thr:
0
0
8
15
0
0
0
0
50
0
0
0
0
36
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
15
15
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
15
0
0
0
0
8
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _