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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
25.15
Human Site:
S642
Identified Species:
42.56
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S642
E
F
Y
R
R
S
R
S
E
I
V
D
Q
Q
G
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S642
E
F
Y
R
R
S
S
S
E
I
V
D
Q
Q
G
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S837
E
F
Y
R
R
G
R
S
E
I
V
D
Q
Q
G
Dog
Lupus familis
XP_545005
885
101736
S648
E
F
Y
R
R
S
R
S
E
I
V
R
G
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
S642
E
F
Y
L
R
S
R
S
E
I
V
D
G
K
G
Rat
Rattus norvegicus
Q4FZV0
881
101203
S642
E
F
Y
L
R
S
R
S
E
I
V
N
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
G590
S
R
S
E
I
I
R
G
E
G
H
T
M
G
A
Frog
Xenopus laevis
NP_001087135
874
101196
R638
E
F
Y
R
R
S
M
R
E
V
V
A
G
L
G
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
S661
E
F
Y
R
R
S
R
S
D
I
S
E
G
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
R659
K
V
E
T
E
L
Y
R
S
L
R
D
T
P
H
Honey Bee
Apis mellifera
XP_392850
1110
128827
S842
L
G
M
Y
F
L
K
S
L
I
S
K
N
L
K
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
A648
S
Q
V
H
Q
S
I
A
L
K
T
Q
T
L
H
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
V492
Y
V
T
L
Y
I
G
V
I
R
E
I
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
L652
W
T
K
Y
T
G
V
L
I
W
K
N
Q
N
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
73.3
N.A.
N.A.
13.3
60
66.6
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
13.3
66.6
86.6
N.A.
20
20
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
36
0
0
0
% D
% Glu:
58
0
8
8
8
0
0
0
58
0
8
8
0
8
0
% E
% Phe:
0
58
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
15
8
8
0
8
0
0
36
8
58
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
15
% H
% Ile:
0
0
0
0
8
15
8
0
15
58
0
8
0
0
0
% I
% Lys:
8
0
8
0
0
0
8
0
0
8
8
8
0
15
8
% K
% Leu:
8
0
0
22
0
15
0
8
15
8
0
0
0
29
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
8
29
29
0
% Q
% Arg:
0
8
0
43
58
0
50
15
0
8
8
8
0
0
0
% R
% Ser:
15
0
8
0
0
58
8
58
8
0
15
0
0
0
8
% S
% Thr:
0
8
8
8
8
0
0
0
0
0
8
8
15
0
0
% T
% Val:
0
15
8
0
0
0
8
8
0
8
50
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
58
15
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _