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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
20.3
Human Site:
S755
Identified Species:
34.36
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S755
C
L
Y
E
E
P
V
S
E
L
L
R
R
C
G
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S755
C
L
Y
E
E
P
V
S
E
L
L
R
R
C
G
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S950
R
L
Y
E
E
P
V
S
E
L
L
R
R
C
G
Dog
Lupus familis
XP_545005
885
101736
P761
L
L
Y
E
E
F
V
P
I
L
L
E
N
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
S755
V
L
F
Q
M
P
V
S
E
L
L
K
R
C
R
Rat
Rattus norvegicus
Q4FZV0
881
101203
S755
V
L
F
Q
M
P
V
S
K
L
L
K
R
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
A699
I
Y
K
E
S
I
N
A
L
L
E
R
C
R
N
Frog
Xenopus laevis
NP_001087135
874
101196
P750
Q
I
Y
T
E
P
I
P
E
L
L
R
R
C
Q
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
S775
L
V
F
Q
Q
S
M
S
A
L
L
S
Q
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
I772
G
V
Q
Y
D
K
V
I
A
I
S
D
L
L
Q
Honey Bee
Apis mellifera
XP_392850
1110
128827
I986
R
S
Y
F
H
S
N
I
T
I
G
A
N
V
V
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
G776
S
S
E
V
L
K
T
G
I
T
F
S
K
I
T
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
A601
F
G
Q
S
Q
M
L
A
Q
I
Q
R
H
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
Y814
A
V
M
V
G
S
R
Y
E
L
E
V
N
V
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
93.3
60
N.A.
60
53.3
N.A.
N.A.
20
60
33.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
93.3
60
N.A.
80
80
N.A.
N.A.
26.6
73.3
73.3
N.A.
26.6
13.3
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
15
15
0
0
8
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
8
58
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
36
36
0
0
0
43
0
15
8
0
0
0
% E
% Phe:
8
0
22
8
0
8
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
8
0
0
8
0
0
8
0
0
8
0
0
0
36
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
8
8
0
0
0
8
8
15
15
22
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
15
0
0
8
0
0
15
8
0
8
% K
% Leu:
15
43
0
0
8
0
8
0
8
72
58
0
8
8
0
% L
% Met:
0
0
8
0
15
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
0
22
0
15
% N
% Pro:
0
0
0
0
0
43
0
15
0
0
0
0
0
0
0
% P
% Gln:
8
0
15
22
15
0
0
0
8
0
8
0
8
0
15
% Q
% Arg:
15
0
0
0
0
0
8
0
0
0
0
43
43
8
8
% R
% Ser:
8
15
0
8
8
22
0
43
0
0
8
15
0
0
0
% S
% Thr:
0
0
0
8
0
0
8
0
8
8
0
0
0
0
8
% T
% Val:
15
22
0
15
0
0
50
0
0
0
0
8
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
43
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _