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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
25.45
Human Site:
S783
Identified Species:
43.08
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
S783
S
A
D
H
E
L
L
S
P
T
N
Y
H
F
L
Chimpanzee
Pan troglodytes
XP_517370
879
100802
S783
S
A
D
H
E
L
L
S
P
T
N
Y
H
F
L
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
S978
S
A
D
H
E
L
L
S
P
T
N
Y
H
F
L
Dog
Lupus familis
XP_545005
885
101736
S789
S
T
D
S
Q
L
S
S
P
T
N
Y
H
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
S783
S
T
D
K
E
L
F
S
P
T
N
Y
H
F
L
Rat
Rattus norvegicus
Q4FZV0
881
101203
S783
S
T
D
N
E
L
F
S
P
T
N
Y
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
P727
G
E
D
G
L
Q
S
P
M
N
H
H
F
L
S
Frog
Xenopus laevis
NP_001087135
874
101196
S778
I
N
Q
G
Q
P
Y
S
S
R
N
W
H
Y
L
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
S803
S
S
A
A
E
P
I
S
P
H
N
H
I
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
I800
L
R
R
G
Q
D
V
I
S
R
T
H
F
F
P
Honey Bee
Apis mellifera
XP_392850
1110
128827
E1014
L
N
S
T
I
L
N
E
C
Q
F
N
I
T
K
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
E804
S
S
G
V
K
I
H
E
D
V
L
V
P
D
F
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
P629
M
L
Y
L
T
Q
V
P
I
G
L
E
S
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
G842
E
D
E
K
R
D
L
G
L
L
Q
K
L
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
N.A.
6.6
26.6
46.6
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
80
N.A.
80
86.6
N.A.
N.A.
20
46.6
66.6
N.A.
26.6
6.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
8
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
50
0
0
15
0
0
8
0
0
0
0
8
0
% D
% Glu:
8
8
8
0
43
0
0
15
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
8
0
15
65
8
% F
% Gly:
8
0
8
22
0
0
0
8
0
8
0
0
0
8
0
% G
% His:
0
0
0
22
0
0
8
0
0
8
8
22
50
0
0
% H
% Ile:
8
0
0
0
8
8
8
8
8
0
0
0
15
0
0
% I
% Lys:
0
0
0
15
8
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
15
8
0
8
8
50
29
0
8
8
15
0
8
8
58
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
15
0
8
0
0
8
0
0
8
58
8
0
0
0
% N
% Pro:
0
0
0
0
0
15
0
15
50
0
0
0
8
0
8
% P
% Gln:
0
0
8
0
22
15
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
8
0
8
0
0
0
0
15
0
0
0
0
0
% R
% Ser:
58
15
8
8
0
0
15
58
15
0
0
0
8
0
15
% S
% Thr:
0
22
0
8
8
0
0
0
0
43
8
0
0
8
0
% T
% Val:
0
0
0
8
0
0
15
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
43
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _