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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
27.88
Human Site:
T131
Identified Species:
47.18
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
T131
N
R
Y
S
F
D
I
T
N
V
V
R
D
V
N
Chimpanzee
Pan troglodytes
XP_517370
879
100802
T131
N
R
Y
S
F
D
I
T
N
V
V
R
D
V
N
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
T326
N
R
Y
S
F
D
I
T
N
V
V
R
D
V
N
Dog
Lupus familis
XP_545005
885
101736
T137
K
R
Y
S
F
D
I
T
S
V
V
S
N
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
T131
T
G
Y
S
F
D
I
T
N
V
V
K
D
V
N
Rat
Rattus norvegicus
Q4FZV0
881
101203
T131
T
R
Y
S
F
D
V
T
N
V
V
K
D
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
R99
S
Y
A
A
E
Q
S
R
C
H
K
A
Y
S
V
Frog
Xenopus laevis
NP_001087135
874
101196
T128
T
R
Y
T
V
D
V
T
N
I
V
T
K
D
N
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
R145
T
T
D
N
M
F
R
R
Y
D
F
D
V
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
S140
V
R
Y
S
Y
E
V
S
S
L
L
Q
A
E
N
Honey Bee
Apis mellifera
XP_392850
1110
128827
D220
D
S
C
V
S
E
N
D
V
P
L
Q
E
P
N
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
D134
P
Y
H
V
N
V
T
D
I
I
A
L
G
E
N
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
L134
G
M
F
R
R
H
T
L
D
V
T
D
I
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
N.A.
0
46.6
0
N.A.
26.6
6.6
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
13.3
66.6
6.6
N.A.
80
40
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
8
8
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
50
0
15
8
8
0
15
36
8
0
% D
% Glu:
0
0
0
0
8
15
0
0
0
0
0
0
8
15
0
% E
% Phe:
0
0
8
0
43
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
36
0
8
15
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
8
15
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
8
15
8
0
8
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
8
8
0
8
0
43
0
0
0
8
0
72
% N
% Pro:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
50
0
8
8
0
8
15
0
0
0
22
0
0
0
% R
% Ser:
8
8
0
50
8
0
8
8
15
0
0
8
0
8
0
% S
% Thr:
29
8
0
8
0
0
15
50
0
0
8
8
0
8
0
% T
% Val:
8
0
0
15
8
8
22
0
8
50
50
0
8
43
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
58
0
8
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _