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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
36.06
Human Site:
T325
Identified Species:
61.03
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
T325
S
A
K
V
Y
F
R
T
V
E
L
I
E
E
P
Chimpanzee
Pan troglodytes
XP_517370
879
100802
T325
S
A
K
V
Y
F
R
T
V
E
L
I
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
T520
S
A
K
V
Y
F
R
T
V
E
L
I
E
E
P
Dog
Lupus familis
XP_545005
885
101736
T331
S
T
K
V
Y
F
R
T
V
E
L
I
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
T325
A
A
K
V
Y
F
R
T
V
Q
L
I
E
E
G
Rat
Rattus norvegicus
Q4FZV0
881
101203
T325
A
A
K
V
Y
F
R
T
V
Q
L
I
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
S279
V
Q
E
P
I
P
G
S
L
G
L
S
F
Y
F
Frog
Xenopus laevis
NP_001087135
874
101196
S321
T
T
K
I
Y
F
R
S
V
E
L
V
E
E
P
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
T344
Q
R
M
V
A
F
R
T
V
E
L
V
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
T348
S
L
R
V
G
F
R
T
L
D
L
V
E
D
P
Honey Bee
Apis mellifera
XP_392850
1110
128827
T443
H
G
V
D
T
F
A
T
I
L
L
N
A
K
K
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
L330
I
G
F
K
T
V
E
L
V
Q
D
L
I
D
P
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
H181
P
V
Q
H
G
F
C
H
P
N
F
I
R
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
P324
E
S
D
S
W
M
Q
P
F
G
F
R
K
I
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
6.6
66.6
53.3
N.A.
53.3
20
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
26.6
93.3
66.6
N.A.
86.6
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
36
0
0
8
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
8
8
0
0
15
0
% D
% Glu:
8
0
8
0
0
0
8
0
0
43
0
0
58
58
15
% E
% Phe:
0
0
8
0
0
79
0
0
8
0
15
0
8
0
8
% F
% Gly:
0
15
0
0
15
0
8
0
0
15
0
0
0
0
8
% G
% His:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
8
0
0
0
8
0
0
50
8
8
0
% I
% Lys:
0
0
50
8
0
0
0
0
0
0
0
0
8
15
8
% K
% Leu:
0
8
0
0
0
0
0
8
15
8
79
8
0
0
8
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
8
0
0
8
0
8
0
8
8
0
0
0
0
0
58
% P
% Gln:
8
8
8
0
0
0
8
0
0
22
0
0
8
0
0
% Q
% Arg:
0
8
8
0
0
0
65
0
0
0
0
8
8
0
0
% R
% Ser:
36
8
0
8
0
0
0
15
0
0
0
8
0
0
0
% S
% Thr:
8
15
0
0
15
0
0
65
0
0
0
0
0
0
0
% T
% Val:
8
8
8
58
0
8
0
0
65
0
0
22
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _