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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
9.39
Human Site:
T717
Identified Species:
15.9
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
T717
L
H
S
D
Y
S
M
T
L
S
V
R
V
H
T
Chimpanzee
Pan troglodytes
XP_517370
879
100802
T717
L
H
S
D
Y
S
M
T
L
T
V
R
V
H
T
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
T912
L
H
S
D
Y
S
M
T
L
T
V
R
V
H
T
Dog
Lupus familis
XP_545005
885
101736
K723
L
S
S
D
C
K
A
K
L
T
V
R
I
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
Q717
L
H
K
D
H
H
T
Q
L
T
V
R
L
H
H
Rat
Rattus norvegicus
Q4FZV0
881
101203
K717
L
H
K
D
Y
P
T
K
L
T
V
R
L
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
L661
H
T
D
H
K
L
T
L
K
V
I
V
N
S
W
Frog
Xenopus laevis
NP_001087135
874
101196
L712
D
L
T
K
T
I
S
L
Q
L
E
I
K
V
Y
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
K737
Q
S
E
Q
H
S
V
K
A
K
V
K
L
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
P734
C
D
Q
L
E
V
D
P
R
E
L
N
V
V
A
Honey Bee
Apis mellifera
XP_392850
1110
128827
L948
Y
Y
I
E
N
M
N
L
S
I
Y
I
V
S
D
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
N738
D
N
P
Y
L
L
H
N
I
T
V
N
V
Q
M
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
S563
A
S
E
Y
G
V
Q
S
W
P
S
F
Q
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
R776
S
D
K
A
V
I
S
R
N
F
Y
W
L
H
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
93.3
93.3
53.3
N.A.
46.6
53.3
N.A.
N.A.
0
0
13.3
N.A.
6.6
6.6
13.3
0
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
66.6
N.A.
N.A.
6.6
6.6
46.6
N.A.
13.3
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
8
43
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
15
8
8
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
36
0
8
15
8
8
0
0
0
0
0
0
50
8
% H
% Ile:
0
0
8
0
0
15
0
0
8
8
8
15
8
0
0
% I
% Lys:
0
0
22
8
8
8
0
22
8
8
0
8
8
0
0
% K
% Leu:
43
8
0
8
8
15
0
22
43
8
8
0
29
0
15
% L
% Met:
0
0
0
0
0
8
22
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
8
0
8
8
8
0
0
15
8
0
0
% N
% Pro:
0
0
8
0
0
8
0
8
0
8
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
8
8
8
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
43
0
0
8
% R
% Ser:
8
22
29
0
0
29
15
8
8
8
8
0
0
15
8
% S
% Thr:
0
8
8
0
8
0
22
22
0
43
0
0
0
8
29
% T
% Val:
0
0
0
0
8
15
8
0
0
8
58
8
43
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% W
% Tyr:
8
8
0
15
29
0
0
0
0
0
15
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _