KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
21.21
Human Site:
T785
Identified Species:
35.9
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
T785
D
H
E
L
L
S
P
T
N
Y
H
F
L
S
S
Chimpanzee
Pan troglodytes
XP_517370
879
100802
T785
D
H
E
L
L
S
P
T
N
Y
H
F
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
T980
D
H
E
L
L
S
P
T
N
Y
H
F
L
S
S
Dog
Lupus familis
XP_545005
885
101736
T791
D
S
Q
L
S
S
P
T
N
Y
H
F
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
T785
D
K
E
L
F
S
P
T
N
Y
H
F
L
S
S
Rat
Rattus norvegicus
Q4FZV0
881
101203
T785
D
N
E
L
F
S
P
T
N
Y
H
F
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
N729
D
G
L
Q
S
P
M
N
H
H
F
L
S
S
L
Frog
Xenopus laevis
NP_001087135
874
101196
R780
Q
G
Q
P
Y
S
S
R
N
W
H
Y
L
S
S
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
H805
A
A
E
P
I
S
P
H
N
H
I
F
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
R802
R
G
Q
D
V
I
S
R
T
H
F
F
P
S
S
Honey Bee
Apis mellifera
XP_392850
1110
128827
Q1016
S
T
I
L
N
E
C
Q
F
N
I
T
K
N
N
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
V806
G
V
K
I
H
E
D
V
L
V
P
D
F
L
F
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
G631
Y
L
T
Q
V
P
I
G
L
E
S
G
A
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
L844
E
K
R
D
L
G
L
L
Q
K
L
F
S
R
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
13.3
40
53.3
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
26.6
60
66.6
N.A.
40
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
50
0
0
15
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
43
0
0
15
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
8
0
15
65
8
0
8
% F
% Gly:
8
22
0
0
0
8
0
8
0
0
0
8
0
0
0
% G
% His:
0
22
0
0
8
0
0
8
8
22
50
0
0
0
0
% H
% Ile:
0
0
8
8
8
8
8
0
0
0
15
0
0
8
0
% I
% Lys:
0
15
8
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
8
8
50
29
0
8
8
15
0
8
8
58
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
58
8
0
0
0
8
8
% N
% Pro:
0
0
0
15
0
15
50
0
0
0
8
0
8
0
0
% P
% Gln:
8
0
22
15
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
0
15
0
0
0
0
0
8
0
% R
% Ser:
8
8
0
0
15
58
15
0
0
0
8
0
15
72
72
% S
% Thr:
0
8
8
0
0
0
0
43
8
0
0
8
0
0
0
% T
% Val:
0
8
0
0
15
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
43
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _