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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
13.94
Human Site:
T847
Identified Species:
23.59
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
T847
S
D
N
G
F
L
M
T
E
K
T
R
T
I
L
Chimpanzee
Pan troglodytes
XP_517370
879
100802
T847
S
D
N
G
F
L
M
T
E
K
T
R
T
I
L
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
T1042
S
D
N
G
F
L
M
T
E
K
T
R
T
I
L
Dog
Lupus familis
XP_545005
885
101736
T853
S
D
N
G
F
L
M
T
E
R
T
R
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
I847
S
D
N
G
F
L
M
I
R
K
K
L
S
V
L
Rat
Rattus norvegicus
Q4FZV0
881
101203
L847
R
F
S
D
N
G
F
L
M
I
K
K
E
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
E791
D
N
G
F
L
M
M
E
K
R
K
V
V
I
F
Frog
Xenopus laevis
NP_001087135
874
101196
A842
S
D
N
G
F
L
L
A
D
K
T
K
T
V
Y
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
L867
H
F
N
L
N
G
F
L
M
L
S
K
K
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
Y864
E
L
L
K
P
Y
R
Y
T
L
S
E
N
G
F
Honey Bee
Apis mellifera
XP_392850
1110
128827
F1078
S
E
N
G
F
H
M
F
E
N
T
K
K
I
L
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
M868
F
S
D
N
G
F
H
M
I
Q
R
L
R
K
I
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
H693
F
N
T
E
K
C
Y
H
I
T
F
S
L
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
V906
S
D
N
Y
F
S
L
V
P
G
E
S
M
S
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
86.6
N.A.
60
0
N.A.
N.A.
13.3
60
6.6
N.A.
0
60
0
0
P-Site Similarity:
100
100
100
100
N.A.
73.3
20
N.A.
N.A.
40
86.6
20
N.A.
6.6
73.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
50
8
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
8
36
0
8
8
8
0
0
% E
% Phe:
15
15
0
8
58
8
15
8
0
0
8
0
0
0
22
% F
% Gly:
0
0
8
50
8
15
0
0
0
8
0
0
0
8
0
% G
% His:
8
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
15
8
0
0
0
36
8
% I
% Lys:
0
0
0
8
8
0
0
0
8
36
22
29
15
8
0
% K
% Leu:
0
8
8
8
8
43
15
15
0
15
0
15
8
8
43
% L
% Met:
0
0
0
0
0
8
50
8
15
0
0
0
8
0
0
% M
% Asn:
0
15
65
8
15
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
8
0
8
15
8
29
8
0
0
% R
% Ser:
58
8
8
0
0
8
0
0
0
0
15
15
8
8
8
% S
% Thr:
0
0
8
0
0
0
0
29
8
8
43
0
36
8
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
8
8
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _