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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
28.48
Human Site:
Y481
Identified Species:
48.21
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
Y481
R
P
I
Y
I
K
D
Y
V
T
L
Y
V
K
N
Chimpanzee
Pan troglodytes
XP_517370
879
100802
Y481
R
P
I
Y
I
K
D
Y
V
T
L
Y
V
K
N
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
Y676
R
P
I
Y
I
K
D
Y
V
T
L
Y
V
K
N
Dog
Lupus familis
XP_545005
885
101736
Y487
L
H
T
Y
I
N
D
Y
V
V
L
Y
V
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
Y481
M
K
T
Y
I
D
D
Y
V
T
L
Y
V
K
N
Rat
Rattus norvegicus
Q4FZV0
881
101203
Y481
L
G
T
Y
I
N
D
Y
V
T
L
Y
V
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
V429
K
D
Y
V
M
L
Y
V
K
N
I
R
E
I
V
Frog
Xenopus laevis
NP_001087135
874
101196
Y477
Q
E
V
Y
R
M
D
Y
V
T
L
Y
I
K
T
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
Y500
R
P
L
Y
V
K
D
Y
V
N
L
Y
V
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
R498
G
T
L
F
E
R
D
R
F
E
S
E
Y
R
E
Honey Bee
Apis mellifera
XP_392850
1110
128827
E681
F
L
K
S
V
R
E
E
V
I
Q
N
V
R
R
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
Y487
E
S
Q
Q
V
K
D
Y
V
L
L
Y
Q
R
L
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
V331
M
K
V
G
F
R
K
V
E
L
V
Q
E
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
S491
Y
F
E
T
Q
L
L
S
D
K
D
S
D
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
66.6
N.A.
73.3
66.6
N.A.
N.A.
0
53.3
73.3
N.A.
6.6
13.3
40
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
73.3
66.6
N.A.
N.A.
20
73.3
86.6
N.A.
33.3
40
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
72
0
8
0
8
0
8
8
0
% D
% Glu:
8
8
8
0
8
0
8
8
8
8
0
8
15
0
8
% E
% Phe:
8
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
22
0
43
0
0
0
0
8
8
0
8
8
8
% I
% Lys:
8
15
8
0
0
36
8
0
8
8
0
0
0
58
0
% K
% Leu:
15
8
15
0
0
15
8
0
0
15
65
0
0
0
8
% L
% Met:
15
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
15
0
8
0
0
43
% N
% Pro:
0
29
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
8
8
8
0
0
0
0
0
8
8
8
0
0
% Q
% Arg:
29
0
0
0
8
22
0
8
0
0
0
8
0
22
8
% R
% Ser:
0
8
0
8
0
0
0
8
0
0
8
8
0
0
8
% S
% Thr:
0
8
22
8
0
0
0
0
0
43
0
0
0
0
15
% T
% Val:
0
0
15
8
22
0
0
15
72
8
8
0
58
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
58
0
0
8
65
0
0
0
65
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _